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- Publications
- Influence
Recovery of Postischemic Brain Metabolism and Function Following Treatment with a Free Radical Scavenger and Platelet‐Activating Factor Antagonists
- D. D. Gilboe, D. Kintner, +4 authors N. G. Bazan
- Chemistry, Medicine
- Journal of neurochemistry
- 1 January 1991
Abstract: We have studied the metabolic and functional effects of two new platelet‐activating factor (PAF) antagonists (BN 50726 and BN 50739) and their diluent (dimethyl sulfoxide; DMSO) during… Expand
Stimulation of K+ fluxes by diuretic drugs in human red cells.
- R. Garay, C. Nazaret, +4 authors A. Esanu
- Chemistry, Medicine
- Biochemical pharmacology
- 1 July 1984
Two different families of diuretic drugs--(i) (aryloxy)acetic acid diuretics (ethacrynic acid, tienilic acid and (--)-indacrinone) and (ii) furopyridines [(+/-)-BN 50157 and… Expand
Evidence that mammalian lignans show endogenous digitalis-like activities.
- M. Fagoo, P. Braquet, J. P. Robin, A. Esanu, T. Godfraind
- Biology, Medicine
- Biochemical and biophysical research…
- 13 February 1986
Enterolactone, a lignan that has been identified in biological samples from man and several mammals, shares with ascorbic acid and cardiac glycosides a gamma-butyrolactone. It displaces 3H-ouabain… Expand
Endogenous lignans--a potential endogenous digitalis.
- P. Braquet, N. Senn, J. P. Robin, A. Esanu, R. Garay
- Medicine
- Journal of hypertension. Supplement : official…
- 1 December 1986
Lignans are natural products formed by oxidative dimerization of monomeric phenols. A few were recently discovered in human and animal urine, semen and blood plasma but their role has never been… Expand
Inhibition of the erythrocyte Na+, K+-pump by mammalian lignans.
- P. Braquet, N. Senn, J. P. Robin, A. Esanu, T. Godfraind, R. Garay
- Chemistry, Medicine
- Pharmacological research communications
- 1 March 1986
Several mammalian lignans, particularly enterolactone, 3-oxy-methyl enterolactone and prestegane B are able to inhibit Na+, K+-pump activity in human red cells with IC50 of about 1 mM. The inhibition… Expand
Recent progress in ginkgolide research
- P. Braquet, A. Esanu, E. Buisine, D. Hosford, C. Broquet, M. Koltai
- Medicine
- Medicinal research reviews
- 1 May 1991
Gaps and perspectives of new fluoroquinolones.
The gaps in the present piperazinyl-substituted fluoroquinolones include: (a) gaps in their antibacterial spectrum, varying from one fluoroquinolone to another for… Expand
Cicletanine Improves Myocardial Function Deteriorated by Ischemia/Reperfusion in Isolated Working Rat Hearts
- P. Ferdinandy, M. Koltai, +4 authors P. Braquet
- Medicine
- Journal of cardiovascular pharmacology
- 1 February 1992
Summary The effect of cicletanine, a novel furopyridine antihypertensive drug was compared with that of nitren-dipine, a dihydropyridine slow calcium channel blocker, on cardiac function and… Expand
Effect of BN 50739, a new platelet activating factor antagonist, on ischaemia induced ventricular arrhythmias in isolated working rat hearts.
- M. Koltai, A. Tosaki, D. Hosford, A. Esanu, P. Braquet
- Medicine
- Cardiovascular research
- 1 May 1991
STUDY OBJECTIVE
The aim was to investigate the role of platelet activating factor (PAF) in myocardial ischaemia by using BN 50739, a new specific PAF receptor antagonist with a hetrazepine framework.… Expand
Cicletanine attenuates overdrive pacing‐induced global myocardial ischemia in rabbits: possible role of cardiac cyclic nucleotides
- Z. Szilvássy, I. Jakab, +5 authors J. Lonovics
- Medicine
- Coronary artery disease
- 1 May 1993
BackgroundThis study examined whether cicletanine, an antihypertensive drug with cGMP phosphodiesterase inhibitory effect, could alleviate ventricular overdrive pacing-induced myocardial ischemia in… Expand