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Guidelines on the irritable bowel syndrome: mechanisms and practical management
TLDR
Better ways of identifying which patients will respond to specific treatments are urgently needed for the assessment and management of adult patients with irritable bowel syndrome.
Characteristics of intestinal dendritic cells in inflammatory bowel diseases.
TLDR
In IBD, DCs are activated, their expression of microbial recognition receptors is up-regulated, and more DCs produce pathologically relevant cytokines, likely to be key initiators or perpetuators of the inflammatory response that characterizes IBD.
Initial assessment of urinary and faecal incontinence in adult male and female patients
Triennial review of patient-reported outcome measures and initial assessments associated with incontinence.
Opioid-Induced Constipation: Pathophysiology, Clinical Consequences, and Management
TLDR
The causes, consequences, and management of OIC are reviewed to help clinicians optimise opioid analgesia and judicious use of the various options to manage OIC should allow more patients to benefit from opioids analgesia.
Randomized clinical trial of sacral versus percutaneous tibial nerve stimulation in patients with faecal incontinence
TLDR
Two new treatments for faecal incontinence have been introduced into the NHS: sacral nerve stimulation and percutaneous tibial nerve stimulation.
Effect of acute physical and psychological stress on gut autonomic innervation in irritable bowel syndrome.
TLDR
Acute stress alters gut-specific efferent autonomic innervation in both controls and patients with IBS, although normalization is delayed in IBS.
Gut microbiota and gastrointestinal health: current concepts and future directions
TLDR
This work states that microbiota diversity in the gut plays a critical role in functions that sustain health and is a positive asset in host defenses, and based on basic and clinical research into the impact and consequences of microbiota biodiversity and change on gastrointestinal disorders and diseases, this work concludes that gut microbiota diversity and change arefundamental to human health.
An International Urogynecological Association (IUGA)/International Continence Society (ICS) joint report on the terminology for female anorectal dysfunction
TLDR
A consensus-based Terminology Report for female anorectal dysfunction terminology has been produced aimed at being a significant aid to clinical practice and a stimulus for research.
Age, Gender and Women's Health and the Patient.
TLDR
Although the majority of FGIDs, including globus, rumination syndrome, IBS, bloating, constipation, functional abdominal pain, sphincter of Oddi dyskinesia, pelvic floor dysfunction, and extra-intestinal manifestations, are more prevalent in women than men, functional chest pain, dyspepsia, vomiting, and anorectal pain do not appear to vary by gender.
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