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- Publications
- Influence
Synthesis, antimicrobial, and anti-inflammatory activity, of novel S-substituted and N-substituted 5-(1-adamantyl)-1,2,4-triazole-3-thiols
- E. Al-Abdullah, Hanadi H. Asiri, S. Lahsasni, E. E. Habib, T. Ibrahim, A. El-Emam
- Chemistry, Medicine
- Drug design, development and therapy
- 12 May 2014
The reaction of 5-(1-adamantyl)-4-phenyl-1,2,4-triazoline-3-thione (compound 5) with formaldehyde and 1-substituted piperazines yielded the corresponding N-Mannich bases 6a–f. The reaction of… Expand
Synthesis, antimicrobial, and anti-HIV-1 activity of certain 5-(1-adamantyl)-2-substituted thio-1,3,4-oxadiazoles and 5-(1-adamantyl)-3-substituted aminomethyl-1,3,4-oxadiazoline-2-thiones.
- A. El-Emam, O. Al-Deeb, M. Al-Omar, J. Lehmann
- Chemistry, Medicine
- Bioorganic & medicinal chemistry
- 1 October 2004
The reaction of 5-(1-adamantyl)-1,3,4-oxadiazoline-2-thione 2 with iodoethane, 2-dimethylaminoethyl chloride hydrochloride or 2-piperidinoethyl chloride hydrochloride in ethanolic potassium hydroxide… Expand
Molecular structure, vibrational spectra, NBO, Fukui function, HOMO-LUMO analysis and molecular docking study of 6-[(2-methylphenyl)sulfanyl]-5-propylpyrimidine-2,4(1H,3H)-dione
- H. Alrabiah, S. Muthu, +4 authors A. El-Emam
- Chemistry
- 25 May 2017
Theoretical and experimental FT-IR and FT-Raman vibrational spectral analysis of 6-[(2-methylphenyl)sulfanyl]-5-propylpyrimidine-2,4(1 H ,3 H )-dione have been recorded in the region 4000-400 cm -1… Expand
Determination of lisinopril in dosage forms and spiked human plasma through derivatization with 7-chloro-4-nitrobenzo-2-oxa-1,3-diazole (NBD-Cl) followed by spectrophotometry or HPLC with…
- A. El-Emam, S. Hansen, M. Moustafa, S. M. El-Ashry, D. El-Sherbiny
- Chemistry, Medicine
- Journal of pharmaceutical and biomedical analysis
- 27 January 2004
Two sensitive, simple and specific methods based on spectrophotometry and reversed-phase HPLC with fluorimetric detection are described for the determination of lisinopril in dosage forms as well as… Expand
Synthesis, Antimicrobial, and Anti-inflammatory Activities of Novel 5-(1-Adamantyl)-4-arylideneamino-3-mercapto-1,2,4-triazoles and Related Derivatives
- M. Al-Omar, E. Al-Abdullah, I. A. Shehata, E. E. Habib, T. Ibrahim, A. El-Emam
- Chemistry, Medicine
- Molecules
- 1 April 2010
The reaction of 5-(1-adamantyl)-4-amino-3-mercapto-1,2,4-triazole (5) with various aromatic aldehydes in ethanol or acetic acid yielded the corresponding 4-arylideneamino derivatives 6a–v. Treatment… Expand
Structural and spectroscopic characterization of a novel potential chemotherapeutic agent 3-(1-adamantyl)-1-{[4-(2-methoxyphenyl)piperazin-1-yl]methyl}-4-methyl-1H-1,2,4-triazole-5(4H)-thione by…
- A. El-Emam, Abdul-Malek S. Al-Tamimi, +4 authors L. Sinha
- Chemistry
- 29 August 2012
Abstract Quantum chemical calculations of energy, geometrical structure and vibrational wavenumbers of a novel functionalized triazoline-3-thione compound (a potential chemotherapeutic agent) with… Expand
Synthesis, Antimicrobial and Hypoglycemic Activities of Novel N-(1-Adamantyl)carbothioamide Derivatives
- Ebtehal S. Al-Abdullah, Hanaa M. Al-Tuwaijri, H. M. Hassan, Monirah A. Al-Alshaikh, E. E. Habib, A. El-Emam
- Chemistry, Medicine
- Molecules
- 1 May 2015
The reaction of 1-adamantyl isothiocyanate 4 with the various cyclic secondary amines yielded the corresponding N-(1-adamantyl)carbothioamides 5a–e, 6, 7, 8a–c and 9. Similarly, the reaction of 4… Expand
Adamantane-Isothiourea Hybrid Derivatives: Synthesis, Characterization, In Vitro Antimicrobial, and In Vivo Hypoglycemic Activities
- L. Al-Wahaibi, H. M. Hassan, A. Abo-Kamar, H. Ghabbour, A. El-Emam
- Chemistry, Medicine
- Molecules
- 29 April 2017
A new series of adamantane-isothiourea hybrid derivatives, namely 4-arylmethyl (Z)-N′-(adamantan-1-yl)-morpholine-4-carbothioimidates 7a–e and 4-arylmethyl… Expand
Spectrophotometric determination of propranolol in formulations via oxidative coupling with 3-methylbenzothiazoline-2-one hydrazone.
- A. El-Emam, Fathalla F. Belal, M. Moustafa, S. M. El-Ashry, D. El-Sherbiny, S. Hansen
- Chemistry, Medicine
- Farmaco
- 1 November 2003
A simple spectrophotometric method has been developed for the determination of propranolol hydrochloride in pure as well as in dosage forms. The method is based on the oxidative coupling reaction… Expand
Experimental FT-IR, Laser-Raman and DFT spectroscopic analysis of a potential chemotherapeutic agent 6-(2-methylpropyl)-4-oxo-2-sulfanylidene-1,2,3,4-tetrahydropyrimidine-5-carbonitrile.
- Y. Sert, A. A. Al-Turkistani, O. Al-Deeb, A. El-Emam, F. Ucun, Ç. Çırak
- Chemistry, Medicine
- Spectrochimica acta. Part A, Molecular and…
- 24 February 2014
In this study, the experimental and theoretical vibrational frequencies of a newly synthesized potential chemotherapeutic agent namely,… Expand
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