HZwint-1, a novel human kinetochore component that interacts with HZW10.
The kinetochore localization of HZwint-1 has been confirmed by following GFP fluorescence in HeLa cells transiently transfected with a plasmid encoding a GFP/HZwinter-1 fusion protein, implying that it plays an important role in correct centromere function.
A Single Gene on the Staphylococcal Multiresistance Plasmid pSK1 Encodes a Novel Partitioning System
Findings implicate active partitioning as the probable basis of the activity of orf245, which is therefore redesignated par, and it seems likely that pSK1 par potentially represents the prototype of a novel class of active partitioned systems that are distinguished by their capacity to enhance plasmid segregational stability via a single protein-encoding gene.
An IS257-Derived Hybrid Promoter Directs Transcription of a tetA(K) Tetracycline Resistance Gene in theStaphylococcus aureus Chromosomal mecRegion
Competition studies revealed that a strain carrying the chromosomal tetA(K) determinant exhibited a higher level of fitness in the presence of tetracycline but not in its absence, suggesting that tetrACYcline has been a selective factor in the emergence of strains carrying a cointegrated pT181-like plasmid in their chromosomes.
Molecular diversity of soil basidiomycete communities in northern-central New South Wales, Australia.
Molecular Analysis of pSK1 par: A Novel Plasmid Partitioning System Encoded by Staphylococcal Multiresistance Plasmids.
It is shown that pSK1 Par binds a centromere consisting of seven repeat elements, and this Par-centromere interaction also mediates Par autoregulation, and combined the data provide insight into the molecular properties of a single protein partition system.