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Antimicrobial and cytotoxic agents from Calophyllum inophyllum.
12 known compounds of xanthone derivative, named inoxanthone, together with their structures were established on the basis of spectral evidence and their antibacterial activity and potency against a wide range of micro organisms were evaluated. Expand
Lupeol long-chain fatty acid esters with antimalarial activity from Holarrhena floribunda.
An ethnopharmacological investigation was conducted among the Baka pygmies of Dja biosphere reserve (Cameroon) to collect information on the antimalarial plants used in their daily life, and extracts of H. floribunda showed remarkable inhibitory activity against drug-resistant strains of Plasmodium falciparum. Expand
Cytotoxic isoflavones from Erythrina indica.
Bioassay-directed fractionation of the CH(2)Cl(2)-MeOH (1:1) extract of the stem bark of Erythrina indica, has resulted in the isolation of two new isoflavone derivatives named indicanines D and EExpand
Globulixanthones A and B, two new cytotoxic xanthones with isoprenoid groups from the root bark of Symphonia globulifera.
Bioassay-guided fractionation of a root bark extract of Symphonia globulifera has yielded two new xanthones with isoprenoid units, named globulixanthones A and B, which possess significant cytotoxicity in vitro against the KB cell line. Expand
Prenylated xanthone derivatives with antiplasmodial activity from Allanblackia monticola STANER L.C.
The methanol extract and pure compounds were tested on two strains of Plasmodium falciparum, F32 ( chloroquine sensitive) and FcM29 (chloroquine resistant) and the IC50 values obtained ranged from 0.6 to 8.9 microg/ml. Expand
Indicanines B and C, two isoflavonoid derivatives from the root bark of Erythrina indica.
Two new compounds, a new 3-phenylcoumarin metabolite and a new isoflavone derivative, were isolated from the root bark of Erythrina indica by means of spectroscopic analysis and in vitro antimicrobial spectrum and potencies are reported. Expand
Laurentixanthones A and B, antimicrobial xanthones from Vismia laurentii.
A phytochemical investigation of the constituents of the roots of Vismia laurentii has resulted in the isolation of two xanthone derivatives named laurentixanthone A and B, established by means of spectroscopic methods. Expand
Antimicrobial activity of the methanolic extracts and compounds from Vismia laurentii De Wild (Guttiferae).
Results provide promising baseline information for the potential use of these crude extracts as well as some of the isolated compounds in the treatment of bacterial and fungal infections. Expand
Phenolic metabolites from Erythrina species
From the stem and root bark of Erythrina sigmoidea and E. eriotricha, one new prenylated flavanone, named sigmoidin L, and two new esters of ferulic and isoferulic acid, erythrinassinates C and D,Expand
Globulixanthones C, D and E: three prenylated xanthones with antimicrobial properties from the root bark of Symphonia globulifera.
Two prenylated xanthone derivatives and one bis-xanthone, designated globulixanthone E, have been isolated from the root bark of Symphonia globulifera and have been shown to exhibit in vitro significant antimicrobial activity against a range of micro-organisms. Expand