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Adenosine Diphosphate–Induced Platelet Aggregation Is Associated With P2Y12 Gene Sequence Variations in Healthy Subjects
Background—The adenosine diphosphate (ADP) receptor P2Y12 plays a pivotal role in platelet aggregation, as demonstrated by the benefit conferred by its blockade in patients with cardiovascular… Expand
The proteome and secretome of human arterial smooth muscle cells
Smooth muscle cells (SMCs) play a crucial role in cardiovascular disorders. A differential proteomic approach should help to elucidate SMC dysfunctions involved in these diseases. With this goal in… Expand
Frequency of abdominal aortic aneurysm in patients undergoing coronary artery bypass grafting.
The aims of this study were to clarify the prevalence and the risk factors for unsuspected abdominal aortic aneurysm (AAA) in patients who underwent coronary artery bypass grafting for severe… Expand
An intronic polymorphism in the PAR-1 gene is associated with platelet receptor density and the response to SFLLRN.
Protease-activated receptor 1 (PAR-1), the main thrombin receptor on vascular cells, plays a key role in platelet activation. We examined the range of PAR-1 expression on platelets, obtained twice, 1… Expand
Von Willebrand factor as a biological sensor of blood flow to monitor percutaneous aortic valve interventions.
RATIONALE Percutaneous aortic valve procedures are a major breakthrough in the management of patients with aortic stenosis. Residual gradient and residual aortic regurgitation are major predictors of… Expand
Two‐dimensional maps and databases of the human macrophage proteome and secretome
Macrophages exert a crucial, but still incompletely known, role in complex disorders such inflammatory, immunological, and infectious diseases. A differential proteomic approach should help to… Expand
Quantitative Mass Spectrometry Analysis Using PAcIFIC for the Identification of Plasma Diagnostic Biomarkers for Abdominal Aortic Aneurysm
Background Abdominal aortic aneurysm (AAA) is characterized by increased aortic vessel wall diameter (>1.5 times normal) and loss of parallelism. This disease is responsible for 1–4% mortality… Expand
Profiling of membrane proteins from human macrophages: Comparison of two approaches
Macrophages are involved in various important biological processes and their functions are tightly regulated. Hydrophobic proteins are difficult to analyse by 2‐DE because of their intrinsic tendency… Expand
Meta-Analysis of Abdominal Aortic Aneurysm in Patients With Coronary Artery Disease.
- A. Elkalioubie, S. Haulon, +6 authors A. Dupont
- The American journal of cardiology
- 1 November 2015
The high coronary artery disease (CAD) prevalence in patients with abdominal aortic aneurysm (AAA) is well known. However, the inverse relation has been little explored. We present, based on a… Expand
Abdominal Aortic Aneurysm in Patients with Coronary Artery Disease: A Review Article
Abdominal Aortic Aneurysm (AAA) is defined as a localized and permanent dilatation of the abdominal aorta, beyond 50% of the normal aorta diameter (Schermerhorn, 2009). The prevalence of AAA ranges… Expand