A. Duncan

Publications25
h-index17
Citations3,988
Highly Influential Citations154
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Optical pathlength measurements on adult head, calf and forearm and the head of the newborn infant using phase resolved optical spectroscopy.
We have used an intensity modulated optical spectrometer, which measures the phase shift across tissue experienced by intensity modulated near-infrared light, to determine the absolute optical… Expand
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Gut Microbiota from Twins Discordant for Obesity Modulate Metabolism in Mice
Introduction Establishing whether specific structural and functional configurations of a human gut microbiota are causally related to a given physiologic or disease phenotype is challenging. Twins… Expand
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The Impact of a Consortium of Fermented Milk Strains on the Gut Microbiome of Gnotobiotic Mice and Monozygotic Twins
Metagenomic analyses of gnotobiotic mice and monozygotic twins reveal the effects of eating a popular fermented milk product on their microbiomes. A Yogurt a Day… We all enjoy a tasty yogurt and… Expand
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Sperm-oviduct interaction: induction of capacitation and preferential binding of uncapacitated spermatozoa to oviductal epithelial cells in porcine species.
After mating, inseminated spermatozoa are transported to the oviduct. They attach to and interact with oviductal epithelial cells (OEC). To investigate sperm-OEC interactions, we used… Expand
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Timolol metabolism in man and laboratory anamals.
The two major urinary metabolites of 14C-timolol in man, involving oxidation and hydrolytic cleavage of the morpholine ring, are also observed in both Sprague-Dawley rats and CRCD-1 mice. These are… Expand
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Predictive water loss curves for ram spermatozoa during cryopreservation: comparison with experimental observations.
Calculated curves predicting intracellular water loss during cryopreservation at different cooling rates were calculated from published equations. To compute these curves, basic cell parameters… Expand
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The physiological disposition and metabolism of enalapril maleate in laboratory animals.
N-[1-(S)-carboxy-3-phenylpropyl]-L-alanyl-L-proline (MK-422), is a potent angiotensin I-converting enzyme (ACE) inhibitor, but as a diacid is poorly absorbed in laboratory animals. Enalapril maleate,… Expand
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Electron-capture GLC determination of timolol in human plasma and urine.
A GLC procedure was developed for measuring nanogram quantities of timolol in plasma and urine. The unchanged drug was extracted into heptane-4% isoamyl alcohol from alkalinized plasma or urine,… Expand
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Interspecies differences in stereoselective protein binding and clearance of MK-571.
(+)-3-(((3-(2-(7-chloro-2-quinolinyl)ethenyl)phenyl)((3-(dimethylamino)- 3-oxopropyl)thio)methyl)thio)propanoic acid (MK-571), is a potent and specific antagonist of leukotriene D4 action in vitro… Expand
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In vitro maintenance of boar sperm viability by a soluble fraction obtained from oviductal apical plasma membrane preparations.
Oviductal apical plasma membrane fractions have been successfully used to provide an in vitro model to study the role of direct membrane contact in sperm-oviduct interactions. Apical plasma membrane… Expand
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