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Pro-inflammatory and anti-inflammatory cytokines in human preterm and term cervical ripening.
Cervical ripening is necessary for successful delivery. Since cytokines are believed to be involved in this process, the aim of this study was to investigate possible changes in the mRNA and proteinExpand
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Low molecular weight heparin stimulates myometrial contractility and cervical remodeling in vitro
Objectives. The low molecular weight heparin, Dalteparin, shortens human labor time. The aim of this study was to investigate if the mechanism behind this effect involves myometrial contractility andExpand
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High-mobility group box protein 1 and its signalling receptors in human preterm and term cervix.
The objective of this study was to identify possible changes in mRNA and protein expression of high-mobility group box protein 1 (HMGB1) and its suggested receptors - receptor for advanced glycationExpand
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Preterm Cervical Ripening in humans
Preterm birth (PTB) is the leading cause of neonatal mortality and morbidity. Despite the current treatment procedures, the incidence of PTB has not changed in the past thirty years. IncompleteExpand
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The preterm cervix reveals a transcriptomic signature in the presence of premature prelabor rupture of membranes
BACKGROUND: Premature prelabor rupture of fetal membranes accounts for 30% of all premature births and is associated with detrimental long‐term infant outcomes. Premature cervical remodeling,Expand
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Does low molecular weight heparin shorten term labor?
Dalteparin, a low molecular weight heparin (LMWH), is given to pregnant women with thrombotic disorders. Clinical observations together with the documented changes of heparan sulfate proteoglycans inExpand
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Different secretion patterns of matrix metalloproteinases and IL-8 and effect of corticotropin-releasing hormone in preterm and term cervical fibroblasts
The aims of the present study were to compare the levels of mRNA and protein expression of matrix metalloproteinase (MMP)-1, -3, -8 and -9 in human cervical tissue in preterm and term labor as wellExpand
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Negative Emotions and Cytokines in Maternal and Cord Serum at Preterm Birth
Problem  This study investigates whether affectivity differs between mothers delivering preterm and term and whether maternal and umbilical cord serum cytokines differ between these groups. Further,Expand
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Density of Stromal Cells and Macrophages Associated With Collagen Remodeling in the Human Cervix in Preterm and Term Birth
Remodeling of the cervix occurs in advance of labor both at term and at preterm birth. Morphological characteristics associated with remodeling in rodents were assessed in cervix biopsies from womenExpand
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Differences in heparan sulfate production in cervical fibroblast cultures from women undergoing term and preterm delivery
Objective. An extensive remodeling of the human cervical connective tissue occurs throughout pregnancy, with a decrease in the total concentration of collagen and proteoglycans. We hypothesized thatExpand
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