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Neuronal Oscillations in Cortical Networks
TLDR
Recent findings indicate that network oscillations bias input selection, temporally link neurons into assemblies, and facilitate synaptic plasticity, mechanisms that cooperatively support temporal representation and long-term consolidation of information.
Electrical coupling underlies high-frequency oscillations in the hippocampus in vitro
TLDR
It is reported that high-frequency network oscillations are present in rat brain slices in vitro, occurring as a brief series of repetitive population spikes at 150–200 Hz in all hippocampal principal cell layers.
Cellular and Network Mechanisms Underlying Spontaneous Sharp Wave–Ripple Complexes in Mouse Hippocampal Slices
TLDR
A surprisingly strong inhibition of most CA1 pyramidal cells during SPW–R is revealed, suggesting a strong separation between members and non‐members of the network may serve to ensure a high signal‐to‐noise ratio in information processing during sharp wave–ripple complexes.
A functional screen implicates microRNA-138-dependent regulation of the depalmitoylation enzyme APT1 in dendritic spine morphogenesis
TLDR
The results uncover a previously unknown miRNA-dependent mechanism in neurons and demonstrate a previously unrecognized complexity of mi RNA-dependent control of dendritic spine morphogenesis.
Axonal Gap Junctions Between Principal Neurons: A Novel Source of Network Oscillations, and Perhaps Epileptogenesis
TLDR
If axonal gap junctions are important for seizure initiation in humans, there could be practical consequences for antiepileptic therapy: at least one gap junction-blocking compound, carbenoxolone, is already in clinical use (for treatment of ulcer disease), and it crosses the blood-brain barrier.
Cellular correlate of assembly formation in oscillating hippocampal networks in vitro
TLDR
This work used physiological and modeling techniques to analyze neuronal activity in mouse hippocampal slices during spontaneously occurring high-frequency network oscillations to identify participating and nonparticipating neurons.
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