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Joint European League Against Rheumatism and European Renal Association–European Dialysis and Transplant Association (EULAR/ERA-EDTA) recommendations for the management of adult and paediatric lupus…
Recommendations for the management of lupus nephritis were developed using an evidence-based approach followed by expert consensus and there is no evidence to suggest that management of LN should differ in children versus adults.
2019 update of the EULAR recommendations for the management of systemic lupus erythematosus
The updated recommendations provide physicians and patients with updated consensus guidance on the management of SLE, combining evidence-base and expert-opinion, based on emerging new evidence.
Anti-inflammatory and immunosuppressive drugs and reproduction
Benefits of anti-inflammatory, immunosuppressive and biological drugs during pregnancy and lactation, effects of these drugs on male and female fertility and possible long-term effects on infants exposed to drugs antenatally are discussed.
Risk factors for subclinical atherosclerosis in a prospective cohort of patients with systemic lupus erythematosus
In patients with SLE some non-traditional risk factors for atherosclerosis were identified, the most important of which was the cumulative prednisone dose, and the role of some traditional risk factors, such as age and hypertension, was confirmed.
Autophagy in human health and disease.
Accelerated Atherosclerosis in Autoimmune Rheumatic Diseases
Several AIRDs exhibit increased overt cardiovascular disease (CVD) prevalence as well as findings of advanced subclinical atherosclerosis, which may precede the appearance of a clinical disease and thus be a target of early identification and preventive therapy.
Overlap connective tissue disease syndromes.
Effects of belimumab, a B lymphocyte stimulator-specific inhibitor, on disease activity across multiple organ domains in patients with systemic lupus erythematosus: combined results from two phase…
- S. Manzi, J. Sánchez-Guerrero, M. Petri
- Medicine, BiologyAnnals of the rheumatic diseases
- 1 April 2012
Belimumab treatment improved overall SLE disease activity in the most common musculoskeletal and mucocutaneous organ domains and less worsening occurred in the haematological, immunological and renal domains.
Risk of congenital complete heart block in newborns of mothers with anti-Ro/SSA antibodies detected by counterimmunoelectrophoresis: a prospective study of 100 women.
The prevalence of CCHB in newborns of prospectively followed up women already known to be anti-Ro/SSA positive and with known CTD was 2%.
Autoantibodies in Polymyositis and Dermatomyositis
New emerging insights about the clinical and pathophysiologic role of principal autoantibodies in myositis are provided.