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- Publications
- Influence
Acute and chronic toxicity of oxethazaine: a highly potent local anesthetic.
- J. M. Glassman, A. Dervinis, W. Beckfield, J. Seifter
- Medicine
- Toxicology and applied pharmacology
- 1 March 1963
Abstract Oxethazaine, an N -substituted bis-acetamide, represents a new series of powerful local anesthetics exceeding by far the potency of either cocaine, procaine, lidocaine, or dibucaine. Acute… Expand
Bronchodilator activity of the prostaglandins E 1 and E 2 .
- M. Rosenthale, A. Dervinis, J. Kassarich
- Medicine
- The Journal of pharmacology and experimental…
- 1 September 1971
The prostaglandins PGE 1 and PGE 2 and isoproterenol were effective bronchodilators capable of reversing the increased airway resistance and decreased airway compliance induced by cholinergic… Expand
Prostaglandins and anti‐inflammatory drugs in the dog knee joint
- M. Rosenthale, A. Dervinis, J. Kassarich, S. Singer
- Medicine
- The Journal of pharmacy and pharmacology
- 1 February 1972
Alteration in Permeability of Some Membranes by Hyaluronidase and Inhibition of this Effect by Steroids
- J. Seifter, D. Baeder, A. Dervinis
- Biology, Medicine
- Proceedings of the Society for Experimental…
- 1 October 1949
Summary 1. Purified testicular hyaluronidase had no effect on the normal or altered permeability of skeletal muscle, cardiac muscle, or of isolated frog skin. 2. Hyaluronidase strikingly increased… Expand
Bronchodilator and antiallergic effects of thiazinamium chloride in guinea pigs, rats, cats and dogs.
- A. J. Lewis, A. Dervinis, M. Rosenthale
- Medicine
- European journal of pharmacology
- 21 May 1982
This study characterized the in vivo pulmonary pharmacology of thiazinamium chloride administered largely by the aerosol route in different animal species. The compound has greater anticholinergic… Expand
Actions of prostaglandins on the respiratory tract of animals.
- M. Rosenthale, A. Dervinis, D. Strike
- Chemistry, Medicine
- Advances in prostaglandin and thromboxane…
- 1976
Experimental data now strongly suggest that the PGs, by nature of their natural local occurrence and destruction, powerful effects on, and release from lung tissue are important in regulating both… Expand
Bronchodilating activity of forskolin in vitro and in vivo.
- J. Chang, J. M. Hand, S. Schwalm, A. Dervinis, A. J. Lewis
- Chemistry, Medicine
- European journal of pharmacology
- 1 June 1984
The effect of forskolin, a receptor-independent adenylate cyclase activator on acetylcholine (ACh)-, histamine- and leukotriene D4 (LTD4)-induced contractions in isolated tracheal spirals was… Expand
Immunopharmacologic properties of WY-16,922, a new orally effective antiallergic agent.
- M. Rosenthale, A. J. Begany, A. Dervinis, J. Sellstedt, C. Guinosso, M. Gluckman
- Chemistry, Medicine
- The Journal of pharmacology and experimental…
- 1 June 1976
In a series of tests designed to illustrate immune reactions similar to those obtained in atopic disease, Wy-16,922 effectively inhibited reaginic-mediated immunologic reactions in the skin, longs… Expand
Ascaris-induced allergic asthma in the conscious dog: a model for the pharmacologic modulation of immediate type hypersensitivity.
- A. J. Lewis, T. Kirchner, A. Dervinis, M. Rosenthale
- Medicine
- Journal of pharmacological methods
- 1982
A noninvasive method has been described for producing and assessing Ascaris-induced bronchospasm in the conscious dog and the bronchial responsiveness of a colony of Ascaris-sensitive dogs has been… Expand
The pharmacologic profile of wy-41,195, a new orally effective antiallergic agent.
- R. P. Carlson, A. Dervinis, J. DiLuigi, R. Capetola, M. Rosenthale, A. J. Lewis
- Chemistry, Medicine
- Arzneimittel-Forschung
- 1982
[2-Cyano-3-(methylamino)phenylamino]oxoacetic acid, sodium salt (Wy-41,195) was found to be a potent oral inhibitor (viz., ED50, 0.3 mg/kg) of IgE-mediated release in the rat passive cutaneous… Expand