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Endovascular thrombectomy after large-vessel ischaemic stroke: a meta-analysis of individual patient data from five randomised trials
TLDR
Endovascular thrombectomy is of benefit to most patients with acute ischaemic stroke caused by occlusion of the proximal anterior circulation, irrespective of patient characteristics or geographical location, and will have global implications on structuring systems of care to provide timely treatment. Expand
Validity and reliability of a quantitative computed tomography score in predicting outcome of hyperacute stroke before thrombolytic therapy
TLDR
This CT score is simple and reliable and identifies stroke patients unlikely to make an independent recovery despite thrombolytic treatment as well as primary outcomes, including symptomatic intracerebral haemorrhage and 3-month functional outcome. Expand
Thrombectomy within 8 hours after symptom onset in ischemic stroke.
TLDR
Among patients with anterior circulation stroke who could be treated within 8 hours after symptom onset, stent retriever thrombectomy reduced the severity of post-stroke disability and increased the rate of functional independence. Expand
Randomized assessment of rapid endovascular treatment of ischemic stroke.
BACKGROUND Among patients with a proximal vessel occlusion in the anterior circulation, 60 to 80% of patients die within 90 days after stroke onset or do not regain functional independence despiteExpand
Endovascular therapy after intravenous t-PA versus t-PA alone for stroke.
TLDR
The trial showed similar safety outcomes and no significant difference in functional independence with endovascular therapy after intravenous t-PA, as compared with intravenoust-PA alone. Expand
Use of the Alberta Stroke Program Early CT Score (ASPECTS) for assessing CT scans in patients with acute stroke.
TLDR
ASPECTS is a systematic, robust, and practical method that can be applied to different axial baselines and clinician agreement is superior to that of the 1/3 MCA rule. Expand
Ultrasound-enhanced systemic thrombolysis for acute ischemic stroke.
TLDR
In patients with acute ischemic stroke, continuous transcranial Doppler augments t-PA-induced arterial recanalization, with a nonsignificant trend toward an increased rate of recovery from stroke, as compared with placebo. Expand
Magnetic resonance imaging and computed tomography in emergency assessment of patients with suspected acute stroke: a prospective comparison
TLDR
MRI is better than CT for detection of acute ischaemia, and can detect acute and chronic haemorrhage; therefore it should be the preferred test for accurate diagnosis of patients with suspected acute stroke. Expand
CT Angiography Clot Burden Score and Collateral Score: Correlation with Clinical and Radiologic Outcomes in Acute Middle Cerebral Artery Infarct
TLDR
Patients with higher CBS and CS demonstrated smaller pretreatment perfusion defects and final infarct volume and better clinical outcome and independently predicted favorable outcome. Expand
Scientific Rationale for the Inclusion and Exclusion Criteria for Intravenous Alteplase in Acute Ischemic Stroke: A Statement for Healthcare Professionals From the American Heart Association/American
TLDR
The levels of evidence supporting individual exclusion criteria for intravenous alteplase vary widely and the differential impact of each exclusion criterion varies not only with the evidence base behind it but also with the frequency of the exclusion within the stroke population and the variation in practice among treating clinicians. Expand
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