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Iron metabolism in reticuloendothelial cells.
  • A. Deiss
  • Biology
    Seminars in hematology
  • 1 April 1983
Metabolism of iron within cells of the RE system is less well understood than any other aspect of iron metabolism. Only with respect to the activity of microsomal heme oxygenase does any precise…
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Hemolytic anemia in Wilson's disease.
Abstract Penicillamine therapy was discontinued for a period of 200 days in a patient with Wilson's disease. Copper reaccumulated in the body at the rate of about 0.43 mg/day. Urinary copper remain...
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Sideroblasts, siderocytes, and sideroblastic anemia.
TLDR
Two distinct series of iron-containing erythroid cells have been distinguished: one in which the iron consists of cytoplasmic aggregates of ferritin and the other in which non-ferritin iron is contained within mitochondria (Table 1).
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Circulating siderocytes in human subjects.
TLDR
Increases both in R-S cells and S cells were seen in patients with splenic atrophy or replacement and in splenectomized patients in the presence of hemolysis.
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Long-term therapy of Wilson's disease.
Abstract Five patients with Wilson's disease were treated initially with potassium sulfide and penicillamine and maintained on penicillamine for 9 to 13 years. All patients are now clinically well....
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Circulating reticulocytes in normal adults as determined y the new methylene blue method.
TLDR
In the presence of large numbers of circulating siderocytes, such as may occur following splenectomy, the reticulocyte count by either method may be erroneous andreticulocytes are best enumerated on preparations which have been first stained for reticulum and then counterstained with the Prussian blue stain.
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Ferritin metabolism in reticulated-siderocytes.
TLDR
A reticulocyte to plasma to monocyte ferritin pathway has been described and it is concluded that blood monocytes are capable of taking up soluble ferritIn from the media and converting this into siderotic granules.
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Hematologic Changes in Chronic Arthritis of Mice Induced by Mycoplasma arthritidis 1
Summary The arthritis caused by iv injection of M. arthritidis in mice was found to be associated with neutrophilia and lymphopenia without a change in the total WBC concentration. A mild anemia…
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Treatment of Wilson's disease.
  • A. Deiss
  • Medicine
    Annals of internal medicine
  • 1 September 1983
TLDR
In view of the ample evidence that the symptoms of Wilson's disease are due to damage caused by excess copper, the goal of treatment ofWilson's disease is to increase copper excretion.
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Experimental production of siderocytes.
Erythrocytes containing one or more granules that give a positive Prussian blue reaction for iron were apparently recognized by workers in the nineteenth century (1) but not until 1941 was the term…
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