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Genome sequencing and analysis of the versatile cell factory Aspergillus niger CBS 513.88
TLDR
The filamentous fungus Aspergillus niger is widely exploited by the fermentation industry for the production of enzymes and organic acids, particularly citric acid, and the sequenced genome revealed a large number of major facilitator superfamily transporters and fungal zinc binuclear cluster transcription factors. Expand
Initial Mutations Direct Alternative Pathways of Protein Evolution
TLDR
It is found that a combination of decreased enzymatic activity and lower folding cooperativity underlies negative sign epistasis in the clash between key mutations in the common and deviating lines, demonstrating that epistasis contributes to contingency in protein evolution by amplifying the selective consequences of random mutations. Expand
On the diversity of fungi from soda soils
TLDR
The phylogenetic analyses show that the alkaliphilic trait in filamentous fungi has evolved several times and is spread throughout the Ascomycota, and usually juxtaposes with slime-covered polyphyletic acremonium-, verticillium-, gliocladium-types of asexual morphology, hyphae aggregating in chords, and enclosed fruit bodies. Expand
The social evolution of somatic fusion.
TLDR
It is proposed that fusion within individuals is beneficial, but fusion between individuals on average costly, selecting for non-self recognition (rather than non-kin recognition), and experimental data on fungi are discussed that are consistent with this hypothesis. Expand
Levels of specificity of Xylaria species associated with fungus‐growing termites: a phylogenetic approach
TLDR
It is concluded that termite‐associated Xylaria are specific for fungus‐growing termites, without having specificity for lower taxonomic levels. Expand
Mitotic Recombination Accelerates Adaptation in the Fungus Aspergillus nidulans
TLDR
An experimental study to explore the specific advantages of haploidy or diploidy in the fungus Aspergillus nidulans shows the adaptive significance of mitotic recombination combined with flexibility in the timing of ploidy level transition if sign epistasis is an important determinant of fitness. Expand
Heterokaryon incompatibility blocks virus transfer among natural isolates of black Aspergilli
TLDR
It is shown that somatic compatibility between different strains is exceptional in natural populations of the asexual black Aspergilli, and horizontal transfer of mycoviruses only occurs between the (very rare) compatible combinations of strains. Expand
Biology and genetics of vegetative incompatibility in fungi
TLDR
VI in fungi as a paradigm for allorecognition in genetically tractable simple eukaryotic species holds great promise to gain a better understanding of the general principles that govern the evolution of nonself recognition systems. Expand
In-host adaptation and acquired triazole resistance in Aspergillus fumigatus: a dilemma for clinical management.
TLDR
The hypothesis is that the current diagnostic tools and treatment strategies do not take into account the biology of the fungus and might result in an increased likelihood of fungal persistence in patients, and future research should investigate the genomic dynamics during infection to understand the key factors facilitating adaptation of Aspergillus spp. Expand
Dynamics of dsRNA mycoviruses in black Aspergillus populations.
TLDR
For a stable virus infection frequency in the black Aspergillus population, fitness costs and spontaneous loss should be balanced with new infections, like in killer virus systems in yeast and smut. Expand
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