• Publications
  • Influence
Spatial heterogeneity of the T cell receptor repertoire reflects the mutational landscape in lung cancer
Somatic mutations together with immunoediting drive extensive heterogeneity within non-small-cell lung cancer (NSCLC). Herein we examine heterogeneity of the T cell antigen receptor (TCR) repertoire.Expand
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Pulmonary venous circulating tumor cell dissemination before tumor resection and disease relapse
Approximately 50% of patients with early-stage non-small-cell lung cancer (NSCLC) who undergo surgery with curative intent will relapse within 5 years1,2. Detection of circulating tumor cells (CTCs)Expand
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Creating metadata that work for digital libraries and Google
TLDR
For many years metadata has been recognised as a significant component of the digital information environment. Expand
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Optimising metadata to make high-value content more accessible to Google users
TLDR
This paper proposes some simple and practical measures for bridging the gulf between the Google world and the metadata world in order to make both more effective for information retrieval. Expand
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HILT: A Pilot Terminology Mapping Service with a DDC Spine
TLDR
The role of DDC in the ongoing HILT (High-level Thesaurus) project is discussed. Expand
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55 days : the fall of South Vietnam
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Chemotaxis of catalytic silica–manganese oxide “matchstick” particles
Particles that can undergo directed self-propulsion are desirable for colloidal cargo delivery and self-assembly. Herein we describe the synthesis of silica–manganese oxide “matchstick” colloids thatExpand
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A clonal expression biomarker associates with lung cancer mortality
An aim of molecular biomarkers is to stratify patients with cancer into disease subtypes predictive of outcome, improving diagnostic precision beyond clinical descriptors such as tumor stage1.Expand
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IP3 receptors
  • A. Dawson
  • Medicine, Biology
  • Current Biology
  • 27 May 2003
What are they? Members of a family of intracellular ligand-gated ion channels that allow Ca2+ release from intracellular stores. The endoplasmic reticulum (ER), or specialised regions of it, containsExpand
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Geospatial immune variability illuminates differential evolution of lung adenocarcinoma
Remarkable progress in molecular analyses has improved our understanding of the evolution of cancer cells toward immune escape 1 – 5 . However, the spatial configurations of immune and stromal cells,Expand
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