• Publications
  • Influence
Antiseptics and Disinfectants: Activity, Action, and Resistance
TLDR
Known mechanisms of microbial resistance (both intrinsic and acquired) to biocides are reviewed, with emphasis on the clinical implications of these reports. Expand
Antimicrobial activity and action of silver.
TLDR
This chapter discusses antimicrobial activity and action of silver, one of the native metals and second only to gold in its stability amongst the metals of antiquity, and its salts and complexes with proteins and other macromolecules. Expand
Bacterial spores and chemical sporicidal agents
  • A. D. Russell
  • Biology, Medicine
  • Clinical Microbiology Reviews
  • 1 April 1990
TLDR
Mechanisms of spore resistance to, and the action of, biocides are discussed, and possible means of enhancing antispore activity are considered. Expand
Biocide use and antibiotic resistance: the relevance of laboratory findings to clinical and environmental situations.
  • A. D. Russell
  • Biology, Medicine
  • The Lancet. Infectious diseases
  • 1 December 2003
TLDR
Assessment of biocidal activity by bactericidal testing is more relevant than by determination of minimum inhibitory concentrations and translation of such findings to the clinical and environmental situations to provide evidence of a possible relation between biocide use and clinical antibiotic resistance is difficult and should be viewed with caution. Expand
Bacterial resistance to disinfectants: present knowledge and future problems.
  • A. D. Russell
  • Biology, Medicine
  • The Journal of hospital infection
  • 1 December 1999
TLDR
There is a need to establish conclusively whether there is a clear-cut linkage between antibiotic and biocide resistance in non-sporulating bacteria and whether biocides can select for antibiotic resistance. Expand
Activity and mechanisms of action of selected biocidal agents on Gram-positive and -negative bacteria.
TLDR
Sub-MIC levels of all ingredients did induce subtle effects on the organisms which impacted bacterial growth, even for those which had no true inhibitory effects. Expand
Triclosan and antibiotic resistance in Staphylococcus aureus.
TLDR
The ability of S. aureus to develop resistance to triclosan and the current view that triclassan may have a specific target in Escherichia coli, namely enoyl reductase, underline the need for more research on the mechanisms of action and resistance. Expand
Pharmaceutical Microbiology
Staphylococcus epidermidis is the leading cause of infections relating to implanted medical devices (Rohde et al 2005). In most natural environments, a biofilm consists of a multispecies bacterialExpand
Antimicrobial activity, uses and mechanism of action of glutaraldehyde.
Similarities and differences in the responses of microorganisms to biocides.
  • A. D. Russell
  • Biology, Medicine
  • The Journal of antimicrobial chemotherapy
  • 1 November 2003
Unlike antibiotics, biocides are multi-targeted antimicrobial agents. Several of the damaging effects reported to occur in the most widely studied organisms, bacteria, may also take place to varyingExpand
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