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Genomic signatures of selection at linked sites: unifying the disparity among species
TLDR
The dominant features that could drive differences in linked selection among species are characterized — including roles for selective sweeps being 'hard' or 'soft' — and the concealing effects of demography and confounding genomic variables are characterized. Expand
Divergence times in Caenorhabditis and Drosophila inferred from direct estimates of the neutral mutation rate.
  • A. Cutter
  • Biology, Medicine
  • Molecular biology and evolution
  • 1 April 2008
TLDR
Divergence times are inferred among 6 species each of Caenorhabditis and Drosophila, based on thousands of orthologous groups of genes, and direct estimates of the mutation rate from contemporary populations that are corrected for interfering effects of selection are illustrated. Expand
Carotenoid Modulation of Immune Function and Sexual Attractiveness in Zebra Finches
TLDR
All 15 specimens housed at MEF, including exemplar specimens of each species, are housed atMEF, which would be inappropriate for strati-graphic methodology. Expand
Nucleotide Polymorphism and Linkage Disequilibrium in Wild Populations of the Partial Selfer Caenorhabditis elegans
  • A. Cutter
  • Biology, Medicine
  • Genetics
  • 1 January 2006
TLDR
A survey of nucleotide polymorphism in six loci from 118 strains of the nematode Caenorhabditis elegans suggests that genetic variation in this species is shaped largely by population subdivision due to self-fertilization coupled with long- and short-range migration between subpopulations. Expand
INBREEDING AND OUTBREEDING DEPRESSION IN CAENORHABDITIS NEMATODES
TLDR
Highly inbred C. remanei showed dramatic reductions in brood size and relative fitness compared to outcrossed individuals, with evidence of both direct genetic and maternal-effect inbreeding depression. Expand
High Nucleotide Polymorphism and Rapid Decay of Linkage Disequilibrium in Wild Populations of Caenorhabditis remanei
TLDR
High levels of diversity and the observation that linkage disequilibrium between pairs of polymorphic sites decays rapidly with distance suggest that C. remanei will provide an excellent system for identifying the genetic targets of natural selection from deviant patterns of polymorphism and linkage Disequilibrium. Expand
Patterns of Nucleotide Polymorphism Distinguish Temperate and Tropical Wild Isolates of Caenorhabditis briggsae
TLDR
The collection of natural isolates is greatly expanded and patterns of nucleotide variation for six loci in 63 strains from three continents are characterized, revealing differentiation between C. briggsae strains found in temperate localities in the northern hemisphere from those sampled near the Tropic of Cancer. Expand
The polymorphic prelude to Bateson-Dobzhansky-Muller incompatibilities.
  • A. Cutter
  • Biology, Medicine
  • Trends in ecology & evolution
  • 1 April 2012
TLDR
The causes and importance of variable reproductive isolation are outlined, and the new challenges of quantifying the relative contributions to reproductive isolation of fixed alleles versus polymorphisms are identified. Expand
Comparative validation of the D. melanogaster modENCODE transcriptome annotation.
TLDR
The vast majority of elements in the D. melanogaster genome annotation are evolutionarily conserved, indicating that the annotation will be an important springboard for functional genetic testing by the Drosophila community. Expand
Patterns of Molecular Evolution in Caenorhabditis Preclude Ancient Origins of Selfing
TLDR
It is concluded that the profound changes in mating behavior, physiology, and developmental mechanisms that accompanied the transition from an obligately outcrossing to a primarily selfing mode of reproduction evolved in the not-too-distant past. Expand
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