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Desensitization and internalization of adenosine A1 receptors in rat brain by in vivo treatment with R-PIA: involvement of coated vesicles.
TLDR
Results demonstrate adenosine A1 receptor desensitization in rat brain by 'in vivo' treatment with R-PIA and suggest a role for coated vesicles in the internalization of G-protein coupled receptors. Expand
Bovine Brain Coated Vesicles Contain Adenosine A1 Receptors. Presence of Adenylate Cyclase Coupled to the Receptor
TLDR
The results of this study support the evidence that adenosine A1 receptors present in coated vesicles are coupled to adenylate cyclase activity through a Gi protein. Expand
Metabotropic glutamate receptor analogues inhibit p[NH]ppG-stimulated phospholipase C activity in bovine brain coated vesicles: involvement of a pertussis toxin-sensitive G-protein.
TLDR
The results support the coupling of mGluRs to a PLC in an inhibitory manner through a pertussis toxin-sensitive G-protein in bovine brain coated vesicles. Expand
The fat cell beta-adrenergic receptor. Purification and characterization of a mammalian beta 1-adrenergic receptor.
TLDR
The purified beta 1-receptor from this mammalian source, composed of a single Mr = 67,000 peptide, is clearly quite distinct from the purified avian beta 1-, amphibian beta 2-, and mammalian beta 2-adrenergic receptors described by others. Expand
Coordination of glucose metabolism and NADPH formation in the adipose tissue and mammary gland during the lactation-weaning transition.
TLDR
The capacity of fat cells from 48-hour weaned mid-lactating rats to synthesize fatty acids from (1- 14C)-glucose and (6-14C)- glucose was markedly increased and the activities of the lipogenic enzymes in adipose tissue were very low during lactation but increased rapidly after weaning. Expand
Roles of cAMP and free fatty acids on the activity of the hexose monophosphate shunt
TLDR
It is concluded that glucose oxidation through hexose monophosphate shunt, activation of lipolysis and triacylglycerol synthesis in isolated rat fat cells by lipolytic agents occurs by a mechanism(s) that depend on intracellular free fatty acids levels. Expand
Characterization of metabotropic glutamate receptors coupled to a pertussis toxin sensitive G‐protein in bovine brain coated vesicles
TLDR
Results indicate the presence of metabotropic glutamate receptors in coated vesicles and its coupling to a pertussis toxin sensitive G‐protein. Expand
Coupling of adenosine A1 receptors to a G-protein in coated vesicles isolated from bovine brain: presence of pertussis and cholera toxin substrates.
TLDR
Results confirm the presence of GTP binding proteins (alpha Gi and alpha Gs) in coated vesicles isolated from bovine brain. Expand
The GABAa receptor complex in the developing chick optic tectum: Ontogeny of [3H]muscimol, [3H]flunitrazepam and [35S]TBPS binding sites
TLDR
The GABA(A) receptor complex reaches a maximum of expression, relative to total membrane protein, immediately after hatching, suggesting that the tectal GABAergic system may be instrumental in damping the effects of sudden exposure to light of the chick visual system upon eye opening. Expand
G-protein-coupled A1 adenosine receptors in coated vesicles of mammalian brain: characterization by radioligand binding and photoaffinity labelling.
TLDR
Results confirm that A1 receptors in coated vesicles are coupled to a G-protein, and it appears that the A1 receptor systems in coatedVesicles and in plasma membranes are identical. Expand
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