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Fringe differentially modulates Jagged1 and Delta1 signalling through Notch1 and Notch2
Proteins encoded by the fringe family of genes are required to modulate Notch signalling in a wide range of developmental contexts. Using a cell co-culture assay, we find that mammalian LunaticExpand
Interactions of Eph-related receptors and ligands confer rostrocaudal pattern to trunk neural crest migration
BACKGROUND In the trunk of avian embryos, neural crest migration through the somites is segmental, with neural crest cells entering the rostral half of each somitic sclerotome but avoiding the caudalExpand
Regulation of polarized extension and planar cell polarity in the cochlea by the vertebrate PCP pathway
The mammalian auditory sensory organ, the organ of Corti, consists of sensory hair cells with uniformly oriented stereocilia on the apical surfaces and has a distinct planar cell polarity (PCP)Expand
The abundance of salamanders in forest stands with different histories of disturbance
Pough, F.H., Smith, E.M., Rhodes, D.H. and Collazo, A., 1987. The abundance of salamanders in forest stands with different histories ofdisturbance. For. Ecol. Manage., 20: 1-9. Because of theExpand
Vital dye labelling of Xenopus laevis trunk neural crest reveals multipotency and novel pathways of migration.
Although the Xenopus embryo has served as an important model system for both molecular and cellular studies of vertebrate development, comparatively little is known about its neural crest. Here, weExpand
XASH-3, a novel Xenopus achaete-scute homolog, provides an early marker of planar neural induction and position along the mediolateral axis of the neural plate.
We have isolated a novel Xenopus homolog of the Drosophila achaete-scute genes, called XASH-3. XASH-3 expression is neural specific and is detected as early as stage 11 1/2, making it one of theExpand
Segmental migration of trunk neural crest: time-lapse analysis reveals a role for PNA-binding molecules.
Trunk neural crest cells migrate through the somites in a striking segmental fashion, entering the rostral but not caudal sclerotome, via cues intrinsic to the somites. Attempts to define theExpand
A dual embryonic origin for vertebrate mechanoreceptors.
Neuromasts, the mechanoreceptors of the lateral line system of fishes and aquatic amphibians, have previously been thought to develop exclusively from embryonic epidermal placodes. Use of fateExpand
Distinct roles for hindbrain and paraxial mesoderm in the induction and patterning of the inner ear revealed by a study of vitamin-A-deficient quail.
The hindbrain and cranial paraxial mesoderm have been implicated in the induction and patterning of the inner ear, but the precise role of the two tissues in these processes is still not clear. WeExpand
Wnt-dependent epithelial transitions drive pharyngeal pouch formation.
The pharyngeal pouches, which form by budding of the foregut endoderm, are essential for segmentation of the vertebrate face. To date, the cellular mechanism and segmental nature of such budding haveExpand