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Effects of metformin on gonadotropin-induced ovulation in women with polycystic ovary syndrome.
TLDR
By reducing hyperinsulinism, metformin determines a reduction in intraovarian androgens, which leads to a Reduction in E2 levels and favors orderly follicular growth in response to exogenous gonadotropins. Expand
Clinical, endocrine and metabolic effects of acarbose, an alpha-glucosidase inhibitor, in PCOS patients with increased insulin response and normal glucose tolerance.
TLDR
This is the first report showing a reduction of the acne/seborrhoea score in hyperinsulinaemic patients with PCOS treated with acarbose, and this improvement was associated with a significant decrease of the insulin response to oral glucose load and of LH and androgen serum concentrations and with asignificant rise of sex hormone binding globulin concentration. Expand
Effect of oral contraceptives on markers of hyperandrogenism and SHBG in women with polycystic ovary syndrome.
TLDR
Formulations with DRSP and CMA caused a greater reduction of androgens and a progressive increase in serum concentrations of SHBG than those with DSG and GSD. Expand
Quality of life and sexual function of women affected by endometriosis-associated pelvic pain when treated with dienogest
TLDR
The progressive reduction of the pain syndrome reported by women over the treatment period could contribute to improve the QoL and sexual life of women on DNG. Expand
Insulin-lowering treatment reduces aromatase activity in response to follicle-stimulating hormone in women with polycystic ovary syndrome.
TLDR
Metformin therapy in women with PCOS is associated with a reduction in aromatase activity in response to FSH, which plays a central role in regulating the activity of thecal and granulosa cells. Expand
d-chiro-Inositol and alpha lipoic acid treatment of metabolic and menses disorders in women with PCOS
TLDR
DCI and alpha lipoic acid treatment has been thought because it plays an essential role in mithocondrial specific pathways that generate energy from glucose and its potent effect as antioxidant and might have a strong impact on metabolic profile even with a short-term treatment. Expand
Effects of metformin on adrenal steroidogenesis in women with polycystic ovary syndrome.
TLDR
The administration of metformin to unselected women with PCOS led to a reduction in the adrenal steroidogenesis response to ACTH, which supports the hypothesis that high insulin levels associated with PCos may cause an increase in plasma levels of adrenal androgens. Expand
Benign multicystic mesothelioma and peritoneal inclusion cysts: are they the same clinical and histopathological entities? A systematic review to find an evidence-based management
TLDR
Peritoneal mesothelial cysts are more common than had previously been thought and most authors consider them non-neoplastic; thus the designation of “peritoneal inclusion cyst” is preferable. Expand
Endometriosis: clinical features, MR imaging findings and pathologic correlation
TLDR
MRI represents the best imaging technique for preoperative staging of endometriosis, in order to choose the more appropriate surgical approach and to plan a multidisciplinary team work. Expand
Combined oral contraceptives in women with menstrual migraine without aura.
TLDR
The 24/4 COC regimen is recommended as the preferred treatment for patients suffering from pure menstrual migraine without aura and demonstrated significant reduction in the intensity and duration of menstrual migraine. Expand
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