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Activation of EGFP expression by Cre-mediated excision in a new ROSA26 reporter mouse strain.
TLDR
This new EGFP reporter strain should facilitate a variety of conditional gene-targeting experiments, including the functional studies of hematopoietic cells in lineage-specific knockout mice. Expand
Focal adhesion kinase (pp125FAK) expression, activation and association with paxillin and p50CSK in human metastatic prostate carcinoma
TLDR
Results show that an increase in FAK mRNA and protein, as well as pp125FAK activation and association with signalling proteins, correlates with progression and invasion in human PCa tissues and cells. Expand
Identification of heparin‐binding proteins in bovine seminal plasma
TLDR
It is demonstrated that BSP‐A1, ‐A2, ‑A3, and ‐30‐kDa proteins bind to heparin or glycosaminoglycans and the postulate interaction of these spermatozoa‐bound proteins with gly cosaminoglyCans in the female reproductive tract is postulated. Expand
Apolipoprotein A-I binds to a family of bovine seminal plasma proteins.
TLDR
The binding of bovine seminal plasma proteins to apoA-I suggests some physiological significance in lipoprotein function or vice versa. Expand
Localization of cholesteryl sulfate in human spermatozoa in support of a hypothesis for the mechanism of capacitation.
TLDR
A hypothesis is presented concerning the role of cholesteryl sulfate as a membrane stabilizer and enzyme inhibitor during the maturation of spermatozoa in the epididymis and the cleavage of the sulfate moiety within the female reproductive tract triggers a cascade of events leading to sperm capacitation and fertilization. Expand
Semen selenium and human fertility.
TLDR
The semen Se level appears to be a useful indicator of Se status versus reproductive function, and an optimal range for semen Se is suggested for reproductive performance. Expand
Transforming growth factor beta down-regulates Src family protein tyrosine kinase signaling pathways.
TLDR
It is suggested, for the first time, that TGF beta induces down-regulation of Src family kinases, leading to disruption of the SHC-growth factor receptor-bound protein 2 complex, which may play a crucial role in the negative regulation of Ras. Expand
Human placental steroid sulfatase: purification and properties.
TLDR
Using aged preparations of microsomes and immunoaffinity techniques, steroid sulfatase activity was found to be associated with the fastest migrating minor component, which would suggest that the apparent heterogeneity of purified steroid sulf atase is linked to degradation processes occurring within the microsomal preparations. Expand
Regulation and activation of focal adhesion kinase and paxillin during the adhesion, proliferation, and differentiation of prostatic epithelial cells in vitro and in vivo.
TLDR
Results demonstrate that pp125FAK expression is regulated at the protein and mRNA levels and forms active signaling complexes with paxillin when epithelial cells in contact with ECM proteins are induced to proliferate in vivo and in vitro. Expand
Male infertility associated with round-headed acrosomeless spermatozoa.
TLDR
The rates of chemically induced nuclear chromatin decondensation of round-headed spermatozoa suggest that the acrosome content is not involved in this process. Expand
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