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Biosynthesis, characterization and antimicrobial activity of copper oxide nanoparticles (CONPs) produced using brown alga extract (Bifurcaria bifurcata)
Recently, biosynthesis of nanoparticles has attracted scientists’ attention because of the necessity to develop new clean, cost-effective and efficient synthesis techniques. In particular, metalExpand
Tissue Doppler Imaging Differentiates Physiological From Pathological Pressure-Overload Left Ventricular Hypertrophy in Rats
TLDR
Myocardial contraction and relaxation assessed by TDI were impaired in pressure-overload LVH but not in exercise LVH, therefore, TDI is more sensitive than conventional echocardiography for assessing myocardial dysfunction in Pressure-over load LVH and for predicting early recovery in myocardIAL function after loading conditions normalization. Expand
Long-Term Heart Rate Reduction Induced by the Selective If Current Inhibitor Ivabradine Improves Left Ventricular Function and Intrinsic Myocardial Structure in Congestive Heart Failure
TLDR
In rats with CHF, long-term HRR induced by the selective If inhibitor ivabradine improves LV function and increases stroke volume, preserving cardiac output despite the HRR. Expand
Selenoprotein T Exerts an Essential Oxidoreductase Activity That Protects Dopaminergic Neurons in Mouse Models of Parkinson's Disease
TLDR
The findings indicate that selenoproteins such as SelT play a crucial role in the protection of dopaminergic neurons against oxidative stress and cell death, providing insight into the molecular underpinnings of this stress in PD. Expand
New investigations within the TeO2-WO3 system: phase equilibrium diagram and glass crystallization
The TeO2-WO3 pseudo-binary system was investigated by temperature programmed X-ray diffraction and differential scanning calorimetry (DSC). The investigated samples were prepared by air quenching ofExpand
Dopamine receptor antagonist properties of S 14506, 8-OH-DPAT, raclopride and clozapine in rodents.
TLDR
From these data, it appears that like raclopride, S 14506 displays dopamine antagonist properties by blocking dopamine D2 receptors, however, the psychopharmacological profile of S14506 is closer to that of clozapine than toThat of raclipride, probably as a result of its actions at 5-HT receptors. Expand
Agomelatine(S 20098) antagonizes the penile erections induced by the stimulation of 5-HT2C receptors in Wistar rats
TLDR
Data suggested that the reported effects were not due to the stimulation of melatonin receptors and that, contrary to melatonin, agomelatine exerted 5-HT2C receptor antagonist properties in addition to its agonist activity atmelatonin receptors. Expand
5-HT2C receptors in psychiatric disorders: A review
TLDR
The development of drugs that specifically target 5-HT2C receptors will allow for better understanding of their involvement in the pathophysiology of psychiatric disorders including schizophrenia, anxiety, and depression and the development of agonists that could activate signal transduction pathways leading to better therapeutic efficiency with fewer adverse effects. Expand
The PACAP-regulated gene selenoprotein T is highly induced in nervous, endocrine, and metabolic tissues during ontogenetic and regenerative processes.
TLDR
Data show that SelT induction is associated with ontogenesis, tissue maturation, and regenerative mechanisms, indicating that this PACAP-regulated selenoprotein may play a crucial role in cell growth and activity in nervous, endocrine, and metabolic tissues. Expand
Structure-affinity relationships of halogenated predicentrine and glaucine derivatives at D1 and D2 dopaminergic receptors: halogenation and D1 receptor selectivity.
TLDR
Results suggest that the 2-hydroxy group on the aporphine skeleton may determine a binding mode favoring D(1)-like over D(2)-like receptors, with enhanced affinity when the C-3 position is halogenated. Expand
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