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A dopamine transporter gene functional variant associated with cocaine abuse in a Brazilian sample.
- C. Guindalini, M. Howard, +14 authors G. Breen
- Medicine, Biology
- Proceedings of the National Academy of Sciences…
- 21 March 2006
The dopamine (DA) transporter DAT1 is a major target bound by cocaine in brain. We examined the influence of functional genetic variants in DAT1 on cocaine addiction. Repeat polymorphisms, including… Expand
Human papillomavirus DNA detection in male sexual partners of women with genital human papillomavirus infection.
OBJECTIVES To determine the prevalence of human papillomavirus (HPV) DNA in the male partners of HPV-infected women, assess the concordance of the viral group in the infected pair, define the most… Expand
HIV-infected pregnant women have greater adherence with antiretroviral drugs than non-pregnant women
- M. J. Vaz, S. Barros, +4 authors A. Castelo
- International journal of STD & AIDS
- 1 January 2007
The objective of the study was to evaluate the influence of pregnancy on the level of adherence with antiretroviral (ARV) drugs, in a prospective cohort of 72 pregnant women and 79 non-pregnant… Expand
High prevalence of hepatitis C infection in a Brazilian prison: identification of risk factors for infection.
- T. Guimarães, C. Granato, D. Varella, M. Ferraz, A. Castelo, E. Kallas
- The Brazilian journal of infectious diseases : an…
- 1 June 2001
Hepatitis C virus (HCV) causes infectious hepatitis worldwide. It is transmitted mainly by blood products and sharing of intravenous paraphernalia during illicit drug use. High prevalence rates have… Expand
Nosocomial bloodstream infections caused by Klebsiella pneumoniae: impact of extended-spectrum β-lactamase (ESBL) production on clinical outcome in a hospital with high ESBL prevalence
BackgroundThe frequency of ESBL producing Klebsiella pneumoniae bloodstream infections (BSI) is high in Brazilian hospitals, however little is known regarding what role, if any, resistance plays in… Expand
Genetic Diversity and HIV‐1 Incidence Estimation Among Cocaine Users in São Paulo, Brazil
- M. Turchi, R. Diaz, +6 authors A. Castelo
- Journal of acquired immune deficiency syndromes
- 15 August 2002
Summary: We describe HIV‐1 incidence and the prevalence of genetic subtypes among cocaine users in São Paulo, Brazil. A cross‐sectional HIV‐1 survey was carried out among 839 current cocaine users… Expand
Association study of dopamine D2 and D3 receptor gene polymorphisms with cocaine dependence
- G. Messas, I. Meira-Lima, +5 authors H. Vallada
- Medicine, Psychology
- Psychiatric genetics
- 1 September 2005
Genetic factors play a role in the vulnerability to cocaine dependence. The reinforcing properties of cocaine are related to the dopaminergic system, and, in particular, the dopamine receptors have… Expand
The biological meaning of anti-HBC positive result in blood donors: relation to HBV-DNA and to other serological markers.
- L. Arraes, R. Ximenes, +4 authors A. Castelo
- Biology, Medicine
- Revista do Instituto de Medicina Tropical de Sao…
- 1 June 2003
In order to assess the potential risk of anti-HBc-positive blood donors for post-transfusional hepatitis and to investigate whether other HBV serological markers are capable of identifying the… Expand
Use of a new 'less-sensitive enzyme immunoassay' testing strategy to identify recently infected persons in a Brazilian prison: estimation of incidence and epidemiological tracing.
Tradução e validação de um questionário de avaliação de qualidade de vida em AIDS no Brasil
- Patrícia Coelho de Soárez, Adauto Castelo, Paulo Abrão, William C. Holmes, Rozana Mesquita Ciconelli
OBJETIVO: Traduzir para portugues brasileiro, adaptar culturalmente e avaliar as propriedades psicometricas (validade e confiabilidade) de um questionario de qualidade de vida (HIV/AIDS-Targeted… Expand