A. Caspi

Publications534
h-index143
Citations91,224
Highly Influential Citations4,476
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Role of Genotype in the Cycle of Violence in Maltreated Children
TLDR
A functional polymorphism in the gene encoding the neurotransmitter-metabolizing enzyme monoamine oxidase A was found to moderate the effect of maltreatment, and it was found that Maltreated children with a genotype conferring high levels of MAOA expression were less likely to develop antisocial problems. Expand
Influence of Life Stress on Depression: Moderation by a Polymorphism in the 5-HTT Gene
TLDR
Evidence of a gene-by-environment interaction is provided, in which an individual's response to environmental insults is moderated by his or her genetic makeup. Expand
Influence of life stress on depression: moderation by a polymorphism in the 5-HTT gene.
TLDR
Evidence of a gene-by-environment interaction is provided, in which an individual's response to environmental insults is moderated by his or her genetic makeup. Expand
A gradient of childhood self-control predicts health, wealth, and public safety
TLDR
Following a cohort of 1,000 children from birth to the age of 32 y, it is shown that childhood self-control predicts physical health, substance dependence, personal finances, and criminal offending outcomes, following a gradient of self- control. Expand
Personality development: stability and change.
TLDR
This review examines research about the structure of personality in childhood and in adulthood, with special attention to possible developmental changes in the lower-order components of broad traits. Expand
Males on the life-course-persistent and adolescence-limited antisocial pathways: Follow-up at age 26 years
TLDR
Findings support the theory of life-course-persistent and adolescence-limited antisocial behavior but also extend it, and recommend intervention with all aggressive children and with all delinquent adolescents, to prevent a variety of maladjustments in adult life. Expand
Sex Differences in Antisocial Behaviour: Conduct Disorder, Delinquency, and Violence in the Dunedin Longitudinal Study
List of figures List of tables Preface Acknowledgements 1. Introduction 2. The Dunedin Multidisciplinary Health and Development Study 3. Sex differences in the amount of antisocial behaviour:… Expand
Female and male antisocial trajectories: From childhood origins to adult outcomes
TLDR
Findings support similarities across gender with respect to developmental trajectories of antisocial behavior and their associated childhood origins and adult consequences. Expand
Prior juvenile diagnoses in adults with mental disorder: developmental follow-back of a prospective-longitudinal cohort.
TLDR
Most adult disorders should be reframed as extensions of juvenile disorders, in particular, juvenile conduct disorder is a priority prevention target for reducing psychiatric disorder in the adult population. Expand
Genetic Sensitivity to the Environment: The Case of the Serotonin Transporter Gene and Its Implications for Studying Complex Diseases and Traits
TLDR
The authors evaluate four lines of evidence about the 5-HTT stress-sensitivity hypothesis: observational studies about the serotonin transporter linked polymorphic region (5-HTTLPR), stress sensitivity, and depression in humans, research about one of the most extensive areas of inquiry. Expand
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