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Airway inflammation in mild intermittent and in persistent asthma.
The severity of asthma can be graded from mild intermittent to severe persistent. Airway inflammation is a feature of persistent asthma. We compared several markers of inflammation in mucosalExpand
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Effect of nitrogen dioxide on synthesis of inflammatory cytokines expressed by human bronchial epithelial cells in vitro.
Although studies of nitrogen dioxide (NO2) inhalation, in both animals and humans, have demonstrated that this agent can cause epithelial cell damage and inflammation of the airway epithelium, theExpand
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Cattle and environmental sample-level factors associated with the presence of Salmonella in a multi-state study of conventional and organic dairy farms.
The objective of this study was to evaluate associations between cattle-level factors and environmental samples with the isolation of Salmonella from dairy farms in Minnesota, Wisconsin, Michigan,Expand
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HLA-DR and ICAM-1 expression on bronchial epithelial cells in asthma and chronic bronchitis.
HLA-DR and ICAM-I molecules play an important role in cellular interactions, and their expression can be induced by inflammatory stimuli. We evaluated the spontaneous expression of HLA-DR and ICAM-1Expand
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Different cytokine patterns in bronchial biopsies in asthma and chronic bronchitis.
Bronchial biopsies have made possible the detailed study of the pathology of the airways of humans with respiratory disease. Much data has been accumulated on asthmatics or normal controls but muchExpand
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Airways remodelling in asthma: no doubt, no more?
Asthma is a chronic inflammatory disease of the airways invariably associated with healing. Remodelling of the airways can be demonstrated by the activation of airways macrophages, the release ofExpand
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Human bronchial epithelial cell dysfunction following in vitro exposure to nitrogen dioxide.
Nitrogen dioxide (NO2), is a major air pollutant, that causes bronchoconstriction and bronchial hyperreactivity, and may also lead to damage and inflammation of the airway epithelium. We haveExpand
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Pathophysiology of allergic rhinitis.
Allergy rhinitis results from an IgE-mediated allergy associated with nasal inflammation of variable intensity. The mechanisms of allergic rhinitis have been clarified using nasal challenge withExpand
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Structural and secretory characteristics of bovine lung and skin mast cells: evidence for the existence of heterogeneity
We have examined cells dispersed enzymatically from three different sites in (he bovine lung (tracheal mucosa, bronchial mucosa and parenchyma) and the skin, in order to ascertain whether the bovineExpand
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Functional characteristics of bronchial epithelium obtained by brushing from asthmatic and normal subjects.
Airways epithelial cells may be involved in the pathogenesis of asthma, but their role remains to be determined. Epithelial cells can release large amounts of 15-hydroxy-eicosatetranoic acidExpand
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