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  • Influence
Genotypic differences in ethanol sensitivity in two tests of motor incoordination.
TLDR
Two tasks that have been used to assay incoordination in mice, the balance beam and the grid test, were evaluated to optimize aspects of apparatus and testing procedures for studying genetic differences, indicating a significant influence of genotype on ethanol sensitivity.
Strain differences in three measures of ethanol intoxication in mice: the screen, dowel and grip strength tests
TLDR
The results suggest that different specific versions of a test reflect the influence of different genes, and that genetic influences on different tests were also distinct.
An analysis of the genetics of alcohol intoxication in inbred mice
Withdrawal severity after chronic intermittent ethanol in inbred mouse strains.
TLDR
The chronic intermittent exposure paradigm is sufficient to elicit differential withdrawal responses across nearly all strains, supporting the influence of common genes on all three responses.
Overview of Mouse Assays of Ethanol Intoxication
TLDR
This unit reviews existing tests to assess sensitivity to ethanol intoxication in mice, and recommends several that are simple to implement, and are sensitive to a particular dose range of ethanol.
Ethanol tolerance and withdrawal severity in high drinking in the dark selectively bred mice.
TLDR
Results show that tolerance to Etoh's hypothermic effects may share some common genetic control with reaching high BECs after DID, a finding consistent with other data regarding genetic contributions to EtOH responses.
Observer-rated ataxia: rating scales for assessment of genetic differences in ethanol-induced intoxication in mice.
TLDR
Modest strain mean correlations among behaviors indicate that these behaviors are probably under control of largely different genes and that ataxia rating scales should rate separate behaviors on discrete scales.
Progress in a replicated selection for elevated blood ethanol concentrations in HDID mice
TLDR
Genetic and behavioral characteristics of high Drinking in the Dark mice in comparison with the HS controls are reported, with common genetic influences more important than environmental influences in determining the similarity between BEC and intake for HDID mice.
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