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Validation of proposed diagnostic criteria (the “Budapest Criteria”) for Complex Regional Pain Syndrome
TLDR
This validation study compared current IASP diagnostic criteria for CRPS to proposed new diagnostic criteria (the “Budapest Criteria”) regarding diagnostic accuracy and suggested that inclusion of four distinct CRPS components in the Budapest Criteria contributed to enhanced specificity. Expand
Perioperative Oral Pregabalin Reduces Chronic Pain After Total Knee Arthroplasty: A Prospective, Randomized, Controlled Trial
TLDR
Perioperative pregabalin administration reduces the incidence of chronic neuropathic pain after TKA, with less opioid consumption and better range of motion during the first 30 days of rehabilitation, however, in the doses tested, it is associated with a higher risk of early postoperative sedation and confusion. Expand
Intrathecal Magnesium Prolongs Fentanyl Analgesia: A Prospective, Randomized, Controlled Trial
TLDR
Intrathecal magnesium prolongs spinal opioid analgesia in humans and suggest that the availability of an intrathecal N-methyl-d-aspartate receptor antagonist could be of clinical importance for pain management. Expand
Effects of perioperative administration of a selective cyclooxygenase 2 inhibitor on pain management and recovery of function after knee replacement: a randomized controlled trial.
TLDR
Perioperative use of an inhibitor of cyclooxygenase 2 is an effective component of multimodal analgesia that reduces opioid consumption, pain, vomiting, and sleep disturbance, with improved knee range of motion after TKA. Expand
Ethnic similarities and differences in the chronic pain experience: a comparison of african american, Hispanic, and white patients.
TLDR
The results suggest that ethnic differences in pain, pain-related sequelae, and affective factors may be small when ethnic groups are closely matched on confounding variables. Expand
Predictors for moderate to severe acute postoperative pain after total hip and knee replacement
TLDR
The findings provide clinical guidance for preoperative stratification of patients for more intensive management potentially including education, nursing staffing, and referral to specialised pain management. Expand
Upregulation of Prostaglandin E2 and Interleukins in the Central Nervous System and Peripheral Tissue during and after Surgery in Humans
TLDR
The results suggest that upregulation of prostaglandin E2 and interleukin 6 at central sites is an important component of surgery induced inflammatory response in patients and may influence clinical outcome. Expand
Safeguards to Prevent Neurologic Complications After Epidural Steroid Injections: Consensus Opinions From a Multidisciplinary Working Group and National Organizations
TLDR
Epidural injections of corticosteroids are widely used to treat radicular pain arising from disk herniation or other spinal nerve conditions and are generally associated with only minor adverse effects. Expand
Development of a severity score for CRPS
TLDR
Results indicate the CSS corresponds with and complements currently accepted dichotomous diagnostic criteria for CRPS, and support its validity as an index of CRPS severity, and its utility as an outcome measure in research studies is suggested. Expand
Consensus Guidelines on the Use of Intravenous Ketamine Infusions for Chronic Pain From the American Society of Regional Anesthesia and Pain Medicine, the American Academy of Pain Medicine, and the
TLDR
Evidence supports the use of ketamine for chronic pain, but the level of evidence varies by condition and dose range; larger studies are needed to better quantify efficacy, improve patient selection, refine the therapeutic dose range, determine the effectiveness of nonintravenous ketamine alternatives, and develop a greater understanding of the long-term risks of repeated treatments. Expand
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