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Clinical research with transcranial direct current stimulation (tDCS): Challenges and future directions
A workgroup of researchers in the field was convened to review, discuss, and provide updates and key challenges of tDCS use in clinical research, and some alternative methods to facilitate clinical research on tDCS are proposed. Expand
A systematic review on reporting and assessment of adverse effects associated with transcranial direct current stimulation.
A systematic review and meta-analysis of tDCS clinical trials suggested that some AEs such as itching and tingling were more frequent in the tDCS active group, although this was not statistically significant and a revised adverse effects questionnaire is proposed to be applied in tDCS studies in order to improve systematic reporting of tCS-related AEs. Expand
A systematic review and meta-analysis of clinical studies on major depression and BDNF levels: implications for the role of neuroplasticity in depression.
The results show that BDNF levels are associated with clinical changes in depression; supporting the notion that depression improvement is associated with neuroplastic changes. Expand
The sertraline vs. electrical current therapy for treating depression clinical study: results from a factorial, randomized, controlled trial.
In MDD, the combination of tDCS and sertraline increases the efficacy of each treatment, and tDCS only (but not sERTraline only) was superior to placebo/sham tDCS. Expand
Safety of Transcranial Direct Current Stimulation: Evidence Based Update 2016
Evidence from relevant animal models indicates that brain injury by Direct Current Stimulation (DCS) occurs at predicted brain current densities that are over an order of magnitude above those produced by conventional tDCS. Expand
Working memory improvement with non-invasive brain stimulation of the dorsolateral prefrontal cortex: A systematic review and meta-analysis
Recent studies have used non-invasive brain stimulation (NIBS) techniques, such as repetitive transcranial magnetic stimulation (rTMS) and transcranial direct current stimulation (tDCS), to increaseExpand
Transcranial direct current stimulation (tDCS) in unipolar vs. bipolar depressive disorder
A preliminary study suggests that tDCS is a promising treatment for patients with major depressive disorder and bipolar depressive disorder, and the beneficial effect persisted at one week and one month. Expand
Modulating Human Procedural Learning by Cerebellar Transcranial Direct Current Stimulation
The finding that anodal cerebellar tDCS improves an implicit learning type essential to the development of several motor skills or cognitive activity suggests that the cerebellum has a critical role in procedural learning. Expand
Transcranial direct current stimulation for major depression: an updated systematic review and meta-analysis.
Active tDCS was statistically superior to sham tDCS for the acute depression treatment, although its role as a clinical intervention is still unclear owing to the mixed findings and heterogeneity of the reviewed studies. Expand
A Systematic Review and Meta-Analysis of the Effects of Transcranial Direct Current Stimulation (tDCS) Over the Dorsolateral Prefrontal Cortex in Healthy and Neuropsychiatric Samples: Influence of
A systematic review and meta-analysis of tDCS studies targeting the DLPFC found that healthy participants respond faster, but not more accurate on cognitive tasks after a-tDCS, but increasing the current density and/or charge might be able to enhance response accuracy, particularly in females. Expand