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Selective protection against conidia by mononuclear and against mycelia by polymorphonuclear phagocytes in resistance to Aspergillus. Observations on these two lines of defense in vivo and in vitro
TLDR
Cortisone inhibited the conidiacidal activity of mouse macrophages in vivo and of human or mouse mononuclear phagocytes in vitro and reduced the mobilization of PMN so that the second line of defense was also impaired, indicating that cortisone can break down natural resistance on its own.
Treatment of gram-negative bacteremia and shock with human antiserum to a mutant Escherichia coli.
TLDR
It is concluded that human antiserum to the lipopolysaccharide core can substantially reduce deaths from gram-negative bacteremia.
Protection against gram-negative bacteremia and endotoxemia with human monoclonal IgM antibodies.
TLDR
Findings indicate that monoclonal IgM against LPS endotoxin can neutralize its toxicity in vivo and might be valuable for treatment of patients with Gram-negative bacteremia.
Treatment of Gram-Negative Bacteremia and Shock with Human Antiserum to a Mutant Escherichia coli
TLDR
It is concluded that human antiserum to the lipopolysaccharide core can substantially reduce deaths from gram-negative bacteremia and endotoxin shock.
Killing of Aspergillus spores depends on the anatomical source of the macrophage
TLDR
The ability of alveolar macrophage to kill Aspergillus spores without modulation by T lymphocytes or the generation of oxygen intermediates points out that concepts built on studies of peritoneal macrophages may be misleading and underscores the importance of studying the role of macrophaging in immunity with cells from the appropriate anatomical site.
Induction of immunity against lethal Haemophilus influenzae type b infection by Escherichia coli core lipopolysaccharide.
TLDR
It is demonstrated that immunity to core LPS confers protection against experimental murine HIB infection and provides the framework for a new approach to prevention of human disease from HIB.
Treatment and prevention of intravascular coagulation with antiserum to endotoxin.
TLDR
Findings indicate that protection by antiserum is independent of antibody to O antigen, does not require complement, and prevents the coagulation disturbances induced by endotoxin.
Passive immunization against the local Shwartzman reaction.
TLDR
Results indicate that antiserum prevents the Shwartzman reaction by action against a toxic antigen common to endotoxins from unrelated bacterial genera; that loss of “0” antigenic units may enhance the production of protective antisera; and that accelerated clearance of endotoxin from the circulation is not necessary for protection.
Acanthamoeba meningoencephalitis in a patient with AIDS.
TLDR
La tropisme de A. culbertsoni pour le systeme nerveux de sujets immunodeprimes est confirmed par des infections experimentales chez la souris.
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