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Measurement of the antibiotic susceptibility of Coxiella burnetii using real time PCR.
Molecular evaluation of antibiotic susceptibility of Tropheryma whipplei in axenic medium.
- A. Boulos, J. Rolain, M. Mallet, D. Raoult
- Medicine, BiologyThe Journal of antimicrobial chemotherapy
- 1 February 2005
Co-trimoxazole was effective in vitro, but this activity was due to sulfamethoxazoles alone, and these results were in accordance with the fact that T. whipplei does not contain the encoding gene for dihydrofolate reductase, the target for trimethoprim.
Correlation between Ratio of Serum Doxycycline Concentration to MIC and Rapid Decline of Antibody Levels during Treatment of Q Fever Endocarditis
- J. Rolain, A. Boulos, M. Mallet, D. Raoult
- Medicine, BiologyAntimicrobial Agents and Chemotherapy
- 1 July 2005
A retrospective examination of whether there was any correlation between the ratio of serum concentration to MIC of doxycycline and response to treatment in patients with Q fever endocarditis found no such correlation.
Antibiotic susceptibility of Neochlamydia hartmanellae and Parachlamydia acanthamoebae in amoebae.
Antibiotic Susceptibility of Tropheryma whipplei in MRC5 Cells
This first extensive study on the susceptibilities of three reference strains of Tropheryma whipplei to antibiotic in cell culture by using a real-time PCR assay finds heterogeneity in the susceptibility to imipenem, with one strain being susceptible and the two other strains being resistant.
Molecular Evaluation of Antibiotic Susceptibility: Tropheryma whipplei Paradigm
- F. Masselot, A. Boulos, M. Maurin, J. Rolain, D. Raoult
- BiologyAntimicrobial Agents and Chemotherapy
- 1 May 2003
The analysis of the T. whipplei genome database allowed the identification not only of the gyrA gene but also the parC gene encoding the alpha subunit of the natural fluoroquinolone targets DNA gyrase (GyrA) and topoisomerase IV (ParC), respectively.
A GLIMPSE ON THE USES OF SEAWEEDS IN ISLAMIC SCIENCE AND DAILY LIFE DURING THE CLASSICAL PERIOD
Islamic polities of the classical period recognized the importance of seaweeds in their daily life. Their men of science, craftsmen, and navigators used them for medicinal purposes, manufacturing,…
BISTABLE EQUILIBRIUM POINTS OF MERCURY BODY BURDEN
The purpose of this paper is to show that the body’s response to mercury exposure is hysteretic, i.e. when this feedback of mercury on its main detoxifying agents is strong enough, then mercury body burden has two points of equilibrium: one with normal abilities to detoxify and low levels of mercury and one with inhibited abilities to toxins and high levels of Mercury.
Treatment of Q Fever Endocarditis Rapid Decline of Antibody Levels during Doxycycline Concentration to MIC and Correlation between Ratio of Serum