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Sperm DNA fragmentation: paternal effect on early post-implantation embryo development in ART.
BACKGROUND The relationship between early embryo post-implantation development in couples undergoing assisted reproductive techniques (ARTs) and sperm chromatin alterations has not beenExpand
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Clinical outcome of oocyte cryopreservation after slow cooling with a protocol utilizing a high sucrose concentration.
BACKGROUND Recently, interest in oocyte cryopreservation has steadily increased. Newly developed protocols have dramatically improved survival rates, removing perhaps the major hurdle that hasExpand
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Differential sucrose concentration during dehydration (0.2 mol/l) and rehydration (0.3 mol/l) increases the implantation rate of frozen human oocytes.
Novel protocols have increased survival and fertilization rates of cryopreserved oocytes. Nevertheless, in most cases clinical experiences have been disappointing or contradictory. Human oocytes ofExpand
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Detailed investigation into the cytogenetic constitution and pregnancy outcome of replacing mosaic blastocysts detected with the use of high-resolution next-generation sequencing.
OBJECTIVE To determine the pregnancy outcome potential of mosaic embryos, detected by means of preimplantation genetic screening (PGS) with the use of next-generation sequencing (NGS). DESIGNExpand
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Over 900 oocyte cryopreservation babies born with no apparent increase in congenital anomalies.
Over the past decade, the number of reported live births resulting from oocyte cryopreservation has rapidly increased. To appreciate the true number of children born, verified live births wereExpand
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Clinical relevance of sperm DNA damage in assisted reproduction.
Many studies have shown how a 'paternal effect' can cause repeated assisted reproduction failures. In particular, with increasing experience of intracytoplasmic sperm injection (ICSI), it becameExpand
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What criteria for the definition of oocyte quality?
Although the spermatozoon provides an essential contribution to the generation of a new individual, the developmental fate of the embryo is principally dictated by the oocyte. Oocyte competencies areExpand
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Meiotic spindle imaging in human oocytes frozen with a slow freezing procedure involving high sucrose concentration.
BACKGROUND One of the major concerns derived from the cryopreservation of meiotically mature oocytes is possible damage to the cytoskeletal apparatus, and in particular the meiotic spindle. METHODSExpand
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Endometrial preparation for frozen-thawed embryo transfer with or without pretreatment with gonadotropin-releasing hormone agonist.
OBJECTIVE To test the efficacy of endometrial preparation with exogenous steroids, without pretreatment with gonadotropin-releasing hormone (GnRH) agonist, in women with normal ovarian function. Expand
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Individualizing FSH dose for assisted reproduction using a novel algorithm: the CONSORT study.
The CONSORT dosing algorithm individualizes recombinant human FSH (r-hFSH) doses for assisted reproduction technologies, assigning 37.5 IU increments according to patient characteristics: basal FSH,Expand
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