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Comparison of scanning electron microscopy, dynamic light scattering and analytical ultracentrifugation for the sizing of poly(butyl cyanoacrylate) nanoparticles.
Nanoparticles represent promising carriers for controlled drug delivery. This work focuses on the size and molecular mass characterization of polyalkylcyanoacrylate nanoparticles formed by anionicExpand
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Chemotherapy of brain tumour using doxorubicin bound to surfactant-coated poly(butyl cyanoacrylate) nanoparticles: revisiting the role of surfactants.
Poly(butyl cyanoacrylate) nanoparticles coated with poloxamer 188 (Pluronic) F68) and also, as shown previously, polysorbate 80 (Tween 80) considerably enhance the anti-tumour effect of doxorubicinExpand
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Molecular weights of poly(butyl cyanoacrylate) nanoparticles determined by mass spectrometry and size exclusion chromatography.
Matrix-assisted laser desorption ionisation time-of-flight mass spectrometry (MALDI-TOF MS) and size exclusion chromatography (SEC) were employed to elucidate the chemical composition, mean numberExpand
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Mechanism of Action and Surfactant Influence During Chemotherapy of Brain Tumour Using Doxorubicin-Loaded Poly(Butyl Cyanoacrylate) Nanoparticles
Doxorubicin (Dox) loaded in poly(butyl cyanoacrylate) nanoparticles (PBCA NP) coated with polysorbate 80 or poloxamer 188 produced a high antitumour effect against orthotopic 101/8 glioblas toma inExpand
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PREPARATION OF TEMOZOLOMIDE LOADED POLY(BUTYL CYANOACRYLATE) NANOPARTICLE FOR CHEMOTHERAPY OF BRAIN TUMOR.
Temozolomide (TMZ) is a DNA methylating agent of the imidazotetrazine derivatives. TMZ has a relatively safe toxicity profile in phase I and II trials in adult patients with melanoma and brainExpand
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