A. Book

Publications22
h-index13
Citations953
Highly Influential Citations65
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Autophagic Degradation of the 26S Proteasome Is Mediated by the Dual ATG8/Ubiquitin Receptor RPN10 in Arabidopsis.
Autophagic turnover of intracellular constituents is critical for cellular housekeeping, nutrient recycling, and various aspects of growth and development in eukaryotes. Here we show that autophagy… Expand
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The RAD23 Family Provides an Essential Connection between the 26S Proteasome and Ubiquitylated Proteins in Arabidopsis[W]
This study describes the collection of UBL/UBA domain proteins in Arabidopsis that participate in the ubiquitin/26S proteasome system, with a focus on the RAD23 family. The data point to a specific… Expand
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Aerobic deconstruction of cellulosic biomass by an insect-associated Streptomyces
Streptomyces are best known for producing antimicrobial secondary metabolites, but they are also recognized for their contributions to biomass utilization. Despite their importance to carbon cycling… Expand
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Affinity Purification of the Arabidopsis 26 S Proteasome Reveals a Diverse Array of Plant Proteolytic Complexes*
Selective proteolysis in plants is largely mediated by the ubiquitin (Ub)/proteasome system in which substrates, marked by the covalent attachment of Ub, are degraded by the 26 S proteasome. The 26 S… Expand
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Evolution of substrate specificity in bacterial AA10 lytic polysaccharide monooxygenases
BackgroundUnderstanding the diversity of lignocellulose-degrading enzymes in nature will provide insights for the improvement of cellulolytic enzyme cocktails used in the biofuels industry. Two… Expand
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Cellulolytic Streptomyces Strains Associated with Herbivorous Insects Share a Phylogenetically Linked Capacity To Degrade Lignocellulose
ABSTRACT Actinobacteria in the genus Streptomyces are critical players in microbial communities that decompose complex carbohydrates in the soil, and these bacteria have recently been implicated in… Expand
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Evolution of High Cellulolytic Activity in Symbiotic Streptomyces through Selection of Expanded Gene Content and Coordinated Gene Expression
The evolution of cellulose degradation was a defining event in the history of life. Without efficient decomposition and recycling, dead plant biomass would quickly accumulate and become inaccessible… Expand
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Tripeptidyl Peptidase II. An Oligomeric Protease Complex from Arabidopsis1
The breakdown of most nuclear and cytoplasmic proteins involves their partial cleavage by the 26S proteasome followed by further disassembly to free amino acids by the combined action of endo- and… Expand
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The RPT2 Subunit of the 26S Proteasome Directs Complex Assembly, Histone Dynamics, and Gametophyte and Sporophyte Development in Arabidopsis[W]
This study explores the function of two highly conserved isoforms of the Arabidopsis thaliana 26S proteasome subunit RPT2 that participate in proteasome-mediated protein turnover. The data point to a… Expand
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The antimicrobial potential of Streptomyces from insect microbiomes
Antimicrobial resistance is a global health crisis and few novel antimicrobials have been discovered in recent decades. Natural products, particularly from Streptomyces, are the source of most… Expand
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