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The Range of Intrinsic Frequencies Represented by Medial Entorhinal Cortex Stellate Cells Extends with Age
In both humans and rodents, the external environment is encoded in the form of cognitive maps. Neurons in the medial entorhinal cortex (mEC) represent spatial locations in a sequence of grid-likeExpand
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Contribution of near-threshold currents to intrinsic oscillatory activity in rat medial entorhinal cortex layer II stellate cells.
The temporal lobe is well known for its oscillatory activity associated with exploration, navigation, and learning. Intrinsic membrane potential oscillations (MPOs) and resonance of stellate cellsExpand
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Function and developmental origin of a mesocortical inhibitory circuit
Midbrain ventral tegmental neurons project to the prefrontal cortex and modulate cognitive functions. Using viral tracing, optogenetics and electrophysiology, we found that mesocortical neurons inExpand
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The new KCNQ2 activator 4‐Chlor‐N‐(6‐chlor‐pyridin‐3‐yl)‐benzamid displays anticonvulsant potential
KCNQ2‐5 channels are voltage‐gated potassium channels that regulate neuronal excitability and represent suitable targets for the treatment of hyperexcitability disorders. The effect ofExpand
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Heterogeneous voltage dependence of interneuron resonance in the hippocampal stratum radiatum of adult rats
ANNE BOEHLEN, UWE HEINEMANN, AND CHRISTIAN HENNEBERGER* Institute of Neurophysiology, Charité, Berlin 13347, Germany Bernstein Center for Computational Neuroscience Berlin, Berlin 10115, GermanyExpand
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Effects of XE991, retigabine, losigamone and ZD7288 on kainate-induced theta-like and gamma network oscillations in the rat hippocampus in vitro
Ion currents such as M-currents (I(M)), persistent sodium currents (I(NaP)) and H-currents (I(h)) have been observed in a variety of brain regions, including the hippocampal formation, where storageExpand
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Hierarchical spike clustering analysis for investigation of interneuron heterogeneity
Action potentials represent the output of a neuron. Especially interneurons display a variety of discharge patterns ranging from regular action potential firing to prominent spike clustering orExpand
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Limited contribution of astroglial gap junction coupling to buffering of extracellular K+ in CA1 stratum radiatum
Astrocytes form large networks, in which individual cells are connected via gap junctions. It is thought that this astroglial gap junction coupling contributes to the buffering of extracellular K+Expand
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