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Glucagon-like peptide 1 induces natriuresis in healthy subjects and in insulin-resistant obese men.
Glucagon-like peptide-1-(7-36)-amide (GLP-1) is involved in satiety control and glucose homeostasis. Animal studies suggest a physiological role for GLP-1 in water and salt homeostasis. This study'sExpand
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The allosteric vestibule of a seven transmembrane helical receptor controls G-protein coupling
Seven transmembrane helical receptors (7TMRs) modulate cell function via different types of G proteins, often in a ligand-specific manner. Class A 7TMRs harbour allosteric vestibules in the entranceExpand
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Supporting medication adherence in renal transplantation (SMART): a pilot RCT to improve adherence to immunosuppressive regimens
Abstract:  Background:  Although non‐adherence to an immunosuppressive regimen (NAH) is a major risk factor for poor outcome after renal transplantation (RTx), very few studies have examinedExpand
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Examining assumptions regarding valid electronic monitoring of medication therapy: development of a validation framework and its application on a European sample of kidney transplant patients
BackgroundElectronic monitoring (EM) is used increasingly to measure medication non-adherence. Unbiased EM assessment requires fulfillment of assumptions. The purpose of this study was to determineExpand
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Use of Neoral C2 monitoring: a European consensus
Large‐scale clinical trials using C2 monitoring of cyclosporine (CsA) microemulsion (Neoral) in renal transplant recipients have demonstrated low acute rejection rates and good tolerability with aExpand
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Brachial artery dilatation after arteriovenous fistulae in patients after renal transplantation: a 10-year follow-up with ultrasound scan.
BACKGROUND Dilatation of the artery proximal to arteriovenous fistula (AF) is not well known but is a potential serious complication in patients for renal transplant. METHODS From 1991 until 2001,Expand
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Medication Adherence Assessment: High Accuracy of the New Ingestible Sensor System in Kidney Transplants
Background This open-label single-arm exploratory study evaluated the accuracy of the Ingestible Sensor System (ISS), a novel technology for directly assessing the ingestion of oral medications andExpand
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Distress associated with adverse effects of immunosuppressive medication in kidney transplant recipients.
CONTEXT For kidney transplant patients, a lifelong intake of medication is mandatory. Health care workers' prioritization of adverse effects often differs from that of their patients, althoughExpand
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An automated 'bio-intact' PTH assay: a step towards standardisation and improved correlation with parathyroid function in renal disease.
BACKGROUND Most methods for the determination of parathyroid hormone (PTH) show cross-reactivity with N-truncated forms of PTH. The analytic and diagnostic value of a recently developed automated PTHExpand
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