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Chemical reactivity of the 18F electrophilic reagents from the 18O(p,n) 18F gas target systems.
A comprehensive evaluation of the reactivity of 18F electrophilic fluorinating agents derived from the 18O(p,n)18F reaction conducted in target bodies made of aluminum, silver, copper, nickel, andExpand
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Regioselective radiofluorodestannylation with [18F]F2 and [18F]CH3COOF: a high yield synthesis of 6-[18F]Fluoro-L-dopa.
A protected 6-trimethylstannyl dopa derivative 6 has been synthesized for the first time as a precursor for the preparation of 6-[18F]fluoro-L-dopa. The tin derivative 6 readily reacted withExpand
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Metals suitable for fluorine gas target bodies: first use of aluminum for the production of [18F]F2.
A comprehensive evaluation of different metals (aluminum, silver, copper, nickel, and gold-plated copper) was undertaken for the fabrication of target bodies with straight and conical bore shapes forExpand
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Proton irradiation of [18O]O2: production of [18F]F2 and [18F]F2 + [18F] OF2.
The production of 18F electrophilic reagents via the 18O(p,n)18F reaction has been investigated in small-volume target bodies made of aluminum, copper, gold-plated copper and nickel, having straightExpand
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Identification and quantitation of gaseous compounds of fluorine generated in [18F]F2 target systems.
The first direct evidence for the chemical identity of the electrophilic fluorinating agents generated in 20Ne(d, alpha)18F (single-step), 18O(p,n)18F (single-step and two-step) and 16O(3He2+, p)18FExpand
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Production of [18F]F2 using the 16O(3He,p)18F reaction.
For the first time, the 16O(3He,p)18F reaction has been used for the production of 18F electrophilic reagents. The predominant reactive chemical specie recovered in the single-step postirradiationExpand
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Detection and quantitation of 17F formation during the cyclotron production of 13N.
The positron emitter 17F has been identified for the first time as a radioactive contaminant formed during 13N production. It was determined that 17F made up 18% of the short-lived radioactivityExpand
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Synthese de n-formyl-3,4-di-t-butoxycarbonyloxy-6-(trimethylstannyl)-l-phenylalanine ethyle ester et sa radiofluorodestannylation regioselective en 6-[18f]-fluoro-l-dopa
Un derive de 6-trimethylstannyl dopa protege a ete synthetise pour la preparation de 6-[18F]fluoro-L-dopa en tant que precurseur. Le derive d'etain reagit avec des agents de radiofluorurationExpand