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Targeting the STAT3 signaling pathway in cancer: role of synthetic and natural inhibitors.
Signal transducers and activators of transcription (STATs) comprise a family of cytoplasmic transcription factors that mediate intracellular signaling that is usually generated at cell surfaceExpand
Cancer Prevention and Treatment with Resveratrol: From Rodent Studies to Clinical Trials
  • A. Bishayee
  • Medicine
  • Cancer Prevention Research
  • 1 May 2009
Resveratrol (3,4′,5-trihydroxy-trans-stilbene) is a dietary polyphenol derived from grapes, berries, peanuts, and other plant sources. During the last decade, resveratrol has been shown to possess aExpand
Resveratrol-mediated chemoprevention of diethylnitrosamine-initiated hepatocarcinogenesis: inhibition of cell proliferation and induction of apoptosis.
Hepatocellular carcinoma (HCC) is one of the most common cancers and lethal diseases. In view of the limited treatment and a grave prognosis of liver cancer, preventive control has been emphasized.Expand
Free Radical-Initiated and Gap Junction-Mediated Bystander Effect due to Nonuniform Distribution of Incorporated Radioactivity in a Three-Dimensional Tissue Culture Model
Abstract Bishayee, A., Hill, H. Z., Stein, D., Rao, D. V. and Howell, R. W. Free Radical-Initiated and Gap Junction-Mediated Bystander Effect due to Nonuniform Distribution of IncorporatedExpand
Curcumin and liver cancer: a review.
Primary liver cancer, also known as hepatocellular carcinoma (HCC), is one of the most lethal cancers having worldwide prevalence. Although most HCC cases are reported in the developing countries ofExpand
Triterpenoids as potential agents for the chemoprevention and therapy of breast cancer.
Breast cancer remains a major cause of death in the United States as well as the rest of the world. In view of the limited treatment options for patients with advanced breast cancer, preventive andExpand
Resveratrol in the chemoprevention and treatment of hepatocellular carcinoma.
Hepatocellular carcinoma (HCC) is one of the most common cancers and lethal diseases in the world. Although the majority of HCC cases occur in developing countries of Asia and Africa, the prevalenceExpand
Exosome biogenesis, bioactivities and functions as new delivery systems of natural compounds.
A rapidly growing body of experimental evidence has begun to shed light on the wide ranging molecular mechanisms which modulate intra- and inter-cellular communications. A substantial quantity of theExpand
Resveratrol and liver disease: from bench to bedside and community
Liver diseases incorporate several maladies, which can range from benign histological changes to serious life‐threatening conditions. These may include inborn metabolic disease, primary andExpand
Hepatoprotective activity of carrot (Daucus carota L.) against carbon tetrachloride intoxication in mouse liver.
The effect of carrot extract on carbon tetrachloride (CCl4)-induced acute liver damage was evaluated. The increased serum enzyme levels (viz., glutamate oxaloacetate transaminase, glutamate pyruvateExpand
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