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Targeting the STAT3 signaling pathway in cancer: role of synthetic and natural inhibitors.
Cancer Prevention and Treatment with Resveratrol: From Rodent Studies to Clinical Trials
- A. Bishayee
- BiologyCancer Prevention Research
- 1 May 2009
Directions for future resveratrol research are described to establish its activity and utility as a human cancer preventive and therapeutic drug.
Resveratrol-mediated chemoprevention of diethylnitrosamine-initiated hepatocarcinogenesis: inhibition of cell proliferation and induction of apoptosis.
Exosome biogenesis, bioactivities and functions as new delivery systems of natural compounds.
Resveratrol Suppresses Oxidative Stress and Inflammatory Response in Diethylnitrosamine-Initiated Rat Hepatocarcinogenesis
- A. Bishayee, Kendra F. Barnes, D. Bhatia, A. S. Darvesh, R. T. Carroll
- Biology, MedicineCancer Prevention Research
- 25 May 2010
Results of the present investigation provide evidence that attenuation of oxidative stress and suppression of inflammatory response mediated by Nrf2 could be implicated, at least in part, in the chemopreventive effects of this dietary agent against chemically induced hepatic tumorigenesis in rats.
The Role of Resveratrol in Cancer Therapy
The current focus of this review is resveratrol’s in vivo and in vitro effects in a variety of cancers, and intracellular molecular targets modulated by this polyphenol.
Hepatoprotective activity of carrot (Daucus carota L.) against carbon tetrachloride intoxication in mouse liver.
Resveratrol in the chemoprevention and treatment of hepatocellular carcinoma.
Free Radical-Initiated and Gap Junction-Mediated Bystander Effect due to Nonuniform Distribution of Incorporated Radioactivity in a Three-Dimensional Tissue Culture Model
The results suggest that the bystander effects caused by nonuniform distributions of radioactivity are affected by the fraction of cells that are labeled, and at least a part of these bystanderser effects are initiated by free radicals and are likely to be mediated by gap junctional intercellular communication.
Dietary Plants for the Prevention and Management of Kidney Stones: Preclinical and Clinical Evidence and Molecular Mechanisms
- Mina Cheraghi Nirumand, Marziyeh Hajialyani, A. Bishayee
- Biology, MedicineInternational journal of molecular sciences
- 1 March 2018
The results as presented demonstrate the promising role of dietary plants and phytophenols in the prevention and management of kidney stones.