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Salarin C, a member of the salarin superfamily of marine compounds, is a potent inducer of apoptosis
The experimental approach described herein is an essential step towards identifying the cellular pathway(s) affected by Salarin C and producing potent synthetic derivatives of salarin C with potential future uses as basic research tools and/or drugs and drug leads.
Nardosinanols A-I and lemnafricanol, sesquiterpenes from several soft corals, Lemnalia sp., Paralemnalia clavata, Lemnalia africana, and Rhytisma fulvum fulvum.
Ten new sesquiterpenes, nardosinanols A-I ( 1- 9) and lemnafricanol ( 10), have been isolated from several Kenyan soft corals, i.e., from Lemnalia sp., Paralemnalia clavata, Lemnalia africana, and
Salarins a and B and tulearin a: new cytotoxic sponge-derived macrolides.
Three novel nitrogenous macrolides designated salarin A and B (1 and 2) and tulearin A (3) were isolated from the Madagascar Fascaplysinopsis sp. sponge. The structures of the compounds were
PLA stereocomplexes for controlled release of somatostatin analogue.
  • A. Bishara, A. Domb
  • Chemistry, Biology
    Journal of controlled release : official journal…
  • 20 October 2005
Taumycins A and B, two bioactive lipodepsipeptides from the Madagascar sponge Fascaplysinopsis sp.
Two closely related lipodepsipeptides, taumycins A and B, have been isolated from the Madagascar sponge Fascaplysinopsis sp, and both were toxic to brine shrimp larvae and inhibited growth of the human UT-7 leukemic cell line.
Stereocomplexes of Triblock Poly(lactide‐ PEG2000‐lactide) as Carrier of Drugs
Triblock copolymers of poly(lactide)-poly(ethylene-glycol)-poly(lactide) (ALA-PEG 2000 -PLA) were synthesized by ring-opening polymerization of lactide and PEG 2000 diol as co-catalyst.
Three biscembranoids and their monomeric counterpart cembranoid, a biogenetic Diels-Alder precursor, from the soft coral Sarcophyton elegans.
Dioxanyalolide possesses antibacterial activity against Escherichia coli at a concentration of 1.25 microg/mL and is most likely the dienophile affording, by a Diels-Alder reaction, the four biscembranoids.