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Tissue biodistribution and blood clearance rates of intravenously administered carbon nanotube radiotracers.
The pharmacokinetic parameters of i.v. administered functionalized CNT relevant for various therapeutic and diagnostic applications are described and urine excretion studies using both f-SWNT and functionalized multiwalled CNT revealed that both types ofnanotubes were excreted as intact nanotubes.
Chemistry of carbon nanotubes.
Department of Materials Science, University of Patras, Greece, Theoretical and Physical Chemistry Institute, National Hellenic Research Foundation, and Dipartimento di Scienze Farmaceutiche, Universita di Trieste, Piazzale Europa 1, 34127 Triesteadays.
Functionalized carbon nanotubes for plasmid DNA gene delivery.
Transmission electron microscopy analysis was performed at the microscopy facility of the Institute of Biomedical Problems and was cofinanced by CNRS, R=gion Alsace, Louis Pasteur University, and the Association de la Recherche pour le Cancer.
Binding and condensation of plasmid DNA onto functionalized carbon nanotubes: toward the construction of nanotube-based gene delivery vectors.
The results indicate that all three types of cationic carbon nanotubes are able to condense DNA to varying degrees, indicating that both nanotube surface area and charge density are critical parameters that determine the interaction and electrostatic complex formation between f-CNTs with DNA.
Science and technology roadmap for graphene, related two-dimensional crystals, and hybrid systems.
An overview of the key aspects of graphene and related materials, ranging from fundamental research challenges to a variety of applications in a large number of sectors, highlighting the steps necessary to take GRMs from a state of raw potential to a point where they might revolutionize multiple industries are provided.
Applications of carbon nanotubes in drug delivery.
Translocation of bioactive peptides across cell membranes by carbon nanotubes.
Functionalised carbon nanotubes are able to cross the cell membrane and to accumulate in the cytoplasm or reach the nucleus without being toxic for the cell up to 10 [micro sign]M.