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- Publications
- Influence
Analysis of the karyotypes of four species of the Leptynia attenuata complex (Insecta Phasmatodea)
- A. Bianchi, Patrizia Meliadò
- Biology
- 1998
SUMMARYKaryotypes of several bisexual populations of the Leptynia attenuata complex were analysed. This complex includes four karyotypically differentiated taxa: Leptynia attenuata s.str., Leptynia… Expand
Mutational landscape of primary, metastatic, and recurrent ovarian cancer reveals c-MYC gains as potential target for BET inhibitors
- Charles Q. Li, E. Bonazzoli, +36 authors A. Santin
- Biology, Medicine
- Proceedings of the National Academy of Sciences
- 24 December 2018
Significance Ovarian cancer has the propensity for early dissemination of microscopic metastases, making early detection challenging. Development of treatments for patients with advanced/recurrent… Expand
Serum miRNAs Expression and SNAP-25 Genotype in Alzheimer’s Disease
- S. Agostini, R. Mancuso, +4 authors M. Clerici
- Biology, Medicine
- Front. Aging Neurosci.
- 11 March 2019
MicroRNAs (miRNAs) are small non-coding RNAs that control gene expression by binding their 3′ untranslated region (3′UTR) region; these molecules play a fundamental role in several pathologies,… Expand
Karyological studies of mediterranean stick-insects belonging to the genera Clonopsis and Leptynia (Insecta Phasmatodea)
- A. Bianchi
- Biology
- 1992
SUMMARYKaryotypes of three species of Clonopsis and of various populations of Leptynia hispanica and L. attenuata complexes were analyzed. The taxonomic status of the latter complexes is still… Expand
Modification of sialidase levels and sialoglycoconjugate pattern during erythroid and erytroleukemic cell differentiation
- C. Tringali, L. Anastasia, +6 authors B. Venerando
- Biology, Medicine
- Glycoconjugate Journal
- 1 December 2006
Glycosphingolipids and glycoproteins play pivotal roles in the complex series of events governing cell adhesion and signal transduction. Aberrant glycosilation, typical of tumor cells, represents a… Expand
A novel multiple biomarker panel for the early detection of high-grade serous ovarian carcinoma.
- Chanhee Han, S. Bellone, +21 authors A. Santin
- Medicine
- Gynecologic oncology
- 1 June 2018
INTRODUCTION
Since the majority of patients are diagnosed at an advanced stage, ovarian cancer remains the most lethal gynecologic malignancy. There is no single biomarker with the sensitivity and… Expand
PI3K oncogenic mutations mediate resistance to afatinib in HER2/neu overexpressing gynecological cancers.
- E. Bonazzoli, E. Cocco, +21 authors A. Santin
- Medicine
- Gynecologic oncology
- 1 April 2019
OBJECTIVE
Aberrant expression of HER2/neu and PIK3CA gene products secondary to amplification/mutations are common in high-grade-serous-endometrial (USC) and ovarian-cancers (HGSOC). Because scant… Expand
Whole-exome sequencing of cervical carcinomas identifies activating ERBB2 and PIK3CA mutations as targets for combination therapy
- L. Zammataro, S. Lopez, +42 authors A. Santin
- Biology, Medicine
- Proceedings of the National Academy of Sciences
- 17 October 2019
Significance The development of novel, effective treatments for patients with advanced/recurrent cervical cancer remains an unmet medical need. Using whole-exome sequencing, we identified multiple… Expand
Inhibition of BET Bromodomain Proteins with GS-5829 and GS-626510 in Uterine Serous Carcinoma, a Biologically Aggressive Variant of Endometrial Cancer
- E. Bonazzoli, Federica Predolini, +23 authors A. Santin
- Biology, Medicine
- Clinical Cancer Research
- 25 June 2018
Purpose: Uterine serous carcinoma (USC) is a rare and aggressive variant of endometrial cancer. Whole-exome sequencing (WES) studies have recently reported c-Myc gene amplification in a large number… Expand
Circulatory miR-223-3p Discriminates Between Parkinson’s and Alzheimer’s Patients
- R. Mancuso, S. Agostini, A. Hernis, Milena Zanzottera, A. Bianchi, M. Clerici
- Medicine
- Scientific Reports
- 28 June 2019
MiR-223-3p is involved in the regulation of a broad range of cellular processes and in many types of pathological processes as cancer, autoimmune and inflammatory diseases. MiR-223-3p has been… Expand