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Self Emulsifying Drug Delivery System: A Review
Selfemulsifying drug delivery system has gained more attention due to enhanced oral bio-availability enabling reduction in dose, more consistent temporal profiles of drug absorption, selective targeting of drug(s) toward specific absorption window in GIT, and protection of drugs from the hostile environment in gut.
Recent advances in proton pump inhibitors and management of acid-peptic disorders.
The emphasis has been laid on the role of proton pump inhibitors widely used nowadays for the treatment of gastric acid diseases and the medicinal chemistry aspects and mechanism of action of irreversible PPIs and APAs at molecular levels.
Formulation and Evaluation of Solid Dispersions of Furosemide in Sodium Starch Glycolate
Purpose: This investigation was carried out to determine if a solid dispersion of furosemide in sodium starch glycolate (SSG) would enhance the dissolution properties of the drug. Methods: Solid
Study of Pharmacodynamic Interaction between a Polyherbal Formulation BSL-150 and Metformin
Investigation of the possible herb drug interaction between a proprietary polyherbal formulation BSL- 150 and metformin in streptozotocin-nicotinamide induced diabetes induced in mice found a significant reduction in the blood glucose, liver glycogen content and glycosylated haemoglobin.
Preparation and evaluation of directly compressible forms of mutual prodrugs of ibuprofen
Tablets of mutual prodrugs of ibuprofen, i.e, 'ibuprofen with paracetamol' and 'ibuprofen with salicylamide,' were prepared by direct compression method. The preformulation studies such as flow
Preparation And Characterization Of Mutual Prodrugs Of Ibuprofen
Ibuprofen was esterified with paracetamol and salicylamide to give two mutual prodrugs. The purity of the compounds was confirmed by TLC. Prodrugs were characterized on the basis of elemental
Design, Synthesis and Evaluation of Schiff’s Bases of 4-Chloro-3-coumarin aldehyde as Antimicrobial Agents
4-Chloro-2-oxo-2H-chromene-3-carbaldehyde (2) was reacted with different anilines in rectified spirit as solvent to yield a series of the title compounds i.e. 4-chloro-3-((substituted-phenylimino)
Extractive Spectrophotometric Determination of Omeprazole in Pharmaceutical Preparations
Purpose: To develop a simple, rapid and selective method for the extractive spectrophotometric determination of omeprazole using acidic dyes. Methods: Extractive spectrophotometric determination of
HPTLC Estimation of Cefixime and Cloxacillin in Tablet Dosage Form
A simple, rapid, reliable and accurate HPTLC method has been developed for the quantitative determination of Cefixime and Cloxacillin in bulk and tablets. The drugs were extracted from (Zifi X 200).
Reverse Phase HPLC Method for Determination of Aceclofenac and Paracetamol in Tablet Dosage Form
A simple, rapid and selective HPLC method has been developed for quantitation of aceclofenac and paracetamol from bulk drug and pharmaceutical formulations using a mobile phase consisting mixture of