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Ten years experience with Jorge Lobo's disease in the state of Acre, Amazon region, Brazil.
Jorge Lobo's disease is a cutaneous and subcutaneous mycosis that affects patients in the Amazon region. The number of patients is relatively small, but the real situation of the disease as publicExpand
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Molecular phylogeny of animal pathogen Lacazia loboi inferred from rDNA and DNA coding sequences.
Lacazia loboi is a geographically restricted, uncultivated fungal pathogen of humans and dolphins. Previous investigations using 18S small unit rDNA, chitin synthase 2 and gp43 DNA sequencesExpand
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Genome-Wide Screening of mRNA Expression in Leprosy Patients
Leprosy, an infectious disease caused by Mycobacterium leprae, affects millions of people worldwide. However, little is known regarding its molecular pathophysiological mechanisms. In this study, aExpand
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Correlacao clinicopatologica em 40 casos novos de lobomicose
A lobomicose e micose cutâneo-subcutânea causada pela Lacazia Loboi, fungo nao cultivavel invitro e de terapeutica insatisfatoria, que merece observacoes clinicas e histopatologicas. O objetivo eraExpand
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In vitro and skin lesion cytokine profile in Brazilian patients with borderline tuberculoid and borderline lepromatous leprosy.
OBJECTIVE We investigated the in vitro and skin lesions production of cytokines in non-treated borderline tuberculoid (BT) and borderline lepromatous (BL) patients. PATIENTS AND METHODS SevenExpand
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Immunolocalization of podoplanin in benign odontogenic tumours with and without ectomesenchyme.
OBJECTIVES To investigate podoplanin expression in epithelial odontogenic tumours with and without ectomesenchyme and verify the association between its immunoexpression and proliferative activity inExpand
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Association of TNFSF8 regulatory variants with excessive inflammatory responses but not leprosy per se.
BACKGROUND Type 1 reactions (T1R) affect a considerable proportion of patients with leprosy. In those with T1R, the host immune response pathologically overcompensates for the actual infectiousExpand
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Accidental Jorge Lobo's disease in a worker dealing with Lacazia loboi infected mice: a case report
IntroductionJorge Lobo's disease (Lacaziosis) is a subcutaneous infection of humans living in the Amazon region of Latin America, and in dolphins inhabiting the east coastal areas of the UnitedExpand
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Angiogenesis and Lymphangiogenesis in the Spectrum of Leprosy and Its Reactional Forms
Background Angiogenesis and lymphangiogenesis are the processes of neovascularization that evolve from preexisting blood and lymphatic vessels. There are few studies on angiogenesis and none onExpand
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qPCR detection of Mycobacterium leprae in biopsies and slit skin smear of different leprosy clinical forms.
Leprosy, whose etiological agent is Mycobacterium leprae, is a chronic infectious disease that mainly affects the skin and peripheral nervous system. The diagnosis of leprosy is based on clinicalExpand
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