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Review of community prevalence of depression in later life
A systematic review of community-based studies of the prevalence of depression in later life (55+) found consistent evidence for higher prevalence rates for women and among older people living under adverse socio-economic circumstances.
Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression
A genome-wide association meta-analysis of individuals with clinically assessed or self-reported depression identifies 44 independent and significant loci and finds important relationships of genetic risk for major depression with educational attainment, body mass, and schizophrenia.
Anxiety disorders in later life: a report from the longitudinal aging study Amsterdam
- A. Beekman, M. Bremmer, W. van Tilburg
- Medicine, EducationInternational journal of geriatric psychiatry
- 1 October 1998
The prevalence and risk factors of anxiety disorders in the older (55–85) population of The Netherlands are studied to find out if older people are more likely to suffer from anxiety disorders.
The Netherlands Study of Depression and Anxiety (NESDA): rationale, objectives and methods
- B. Penninx, A. Beekman, R. van Dyck
- PsychologyInternational journal of methods in psychiatric…
- 1 September 2008
The Netherlands Study of Depression and Anxiety (NESDA) is a multi‐site naturalistic cohort study to: (1) describe the long‐term course and consequences of depressive and anxiety disorders, and (2)…
Prevalence and risk indicators of depression in elderly nursing home patients: the AGED study.
Anxiety and depression in later life: Co-occurrence and communality of risk factors.
- A. Beekman, E. de Beurs, A. V. van Balkom, D. Deeg, R. van Dyck, W. van Tilburg
- Psychology, MedicineThe American journal of psychiatry
Although high levels of comorbidity between major depressive Disorder and anxiety disorders were found, comparing risk factors associated with pure major depressive disorder and pure anxiety disorders revealed more differences than similarities.
Analysis of shared heritability in common disorders of the brain
It is demonstrated that, in the general population, the personality trait neuroticism is significantly correlated with almost every psychiatric disorder and migraine, and it is shown that both psychiatric and neurological disorders have robust correlations with cognitive and personality measures.
Duration of major depressive episodes in the general population: Results from the Netherlands Mental Health Survey and Incidence Study (NEMESIS)
- J. Spijker, R. de Graaf, R. Bijl, A. Beekman, J. Ormel, W. Nolen
- Medicine, PsychologyBritish Journal of Psychiatry
- 1 September 2002
Although half of those affected with MDE recovered rapidly, the risk of chronicity (duration 24months or more) was considerable and underlines the necessity of diagnosing and treating those at risk.
Major and minor depression in later life: a study of prevalence and risk factors.
Development of the EURO–D scale – a European Union initiative to compare symptoms of depression in 14 European centres
A two-factor solution seemed appropriate: depression, tearfulness and wishing to die loaded on the first factor (affective suffering), and loss of interest, poor concentration and lack of enjoyment on the second (motivation).