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Clinical practice guidelines by the infectious diseases society of america for the treatment of methicillin-resistant Staphylococcus aureus infections in adults and children.
TLDR
These guidelines discuss the management of a variety of clinical syndromes associated with MRSA disease, including skin and soft tissue infections (SSTI), bacteremia and endocarditis, pneumonia, bone and joint infections, and central nervous system infections. Expand
Clinical practice guidelines by the infectious diseases society of america for the treatment of methicillin-resistant Staphylococcus aureus infections in adults and children: executive summary.
TLDR
These guidelines discuss the management of a variety of clinical syndromes associated with MRSA disease, including skin and soft tissue infections (SSTI), bacteremia and endocarditis, pneumonia, bone and joint infections, and central nervous system infections. Expand
Infective Endocarditis in Adults: Diagnosis, Antimicrobial Therapy, and Management of Complications: A Scientific Statement for Healthcare Professionals From the American Heart Association
TLDR
The recommendations provided in this document are intended to assist in the management of this uncommon but potentially deadly infection and must be used to support and not supplant decisions in individual patient management. Expand
Clinical presentation, etiology, and outcome of infective endocarditis in the 21st century: the International Collaboration on Endocarditis-Prospective Cohort Study.
TLDR
In the early 21st century, IE is more often an acute disease, characterized by a high rate of S aureus infection, and Mortality remains relatively high. Expand
Staphylococcus aureus endocarditis: a consequence of medical progress.
TLDR
Characteristics of patients with S aureus IE vary significantly by region, and further studies are required to determine the causes of regional variation. Expand
Diagnosis and management of infective endocarditis and its complications.
TLDR
The variability in the clinical presentation of IE requires a diagnostic strategy that will be both sensitive for disease detection and specific for its exclusion across all the forms of the disease, and the current literature is reviewed. Expand
Regulation of virulence determinants in vitro and in vivo in Staphylococcus aureus.
TLDR
Sequence alignment and structural data indicate that the SarA protein family could be subdivided into three subfamilies: (1) single-domain proteins; (2) double- domain proteins; and (3) proteins homologous to the MarR protein family. Expand
Necrotizing fasciitis caused by community-associated methicillin-resistant Staphylococcus aureus in Los Angeles.
TLDR
In areas in which community-associated MRSA infection is endemic, empirical treatment of suspected necrotizing fasciitis should include antibiotics predictably active against this pathogen. Expand
Prevention of bacterial endocarditis. Recommendations by the American Heart Association.
TLDR
Major changes were instituted to more clearly define when prophylaxis is or is not recommended, improve practitioner and patient compliance, reduce cost and potential gastrointestinal adverse effects, and approach more uniform worldwide recommendations. Expand
Advances in antimicrobial peptide immunobiology
TLDR
It appears that a relatively limited set of physicochemical features is required for antimicrobial peptide efficacy against a broad spectrum of microbial pathogens. Expand
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