• Publications
  • Influence
Current understanding of molecular and cellular mechanisms in fibroplasia and angiogenesis during acute wound healing.
Cutaneous wound healing ultimately functions to facilitate barrier restoration following injury-induced loss of skin integrity. It is an evolutionarily conserved, multi-cellular, multi-molecularExpand
  • 268
  • 11
Molecular dissection of abnormal wound healing processes resulting in keloid disease
Keloids are locally aggressive scars that typically invade into healthy surrounding skin and cause both physical and psychosocial distress to the patient. These pathological scars occur followingExpand
  • 174
  • 9
  • PDF
Epidemiological Evaluation of Dupuytren’s Disease Incidence and Prevalence Rates in Relation to Etiology
Dupuytren’s Disease (DD) is a common, fibroproliferative disorder affecting the palmar surface of the hands which is often irreversible and progressive. Understanding the epidemiology of DD isExpand
  • 157
  • 8
  • PDF
The Role of Neuromediators and Innervation in Cutaneous Wound Healing.
The skin is densely innervated with an intricate network of cutaneous nerves, neuromediators and specific receptors which influence a variety of physiological and disease processes. There is emergingExpand
  • 37
  • 4
  • PDF
Notch signaling pathway in keloid disease: Enhanced fibroblast activity in a Jagged‐1 peptide‐dependent manner in lesional vs. extralesional fibroblasts
  • F. Syed, A. Bayat
  • Biology, Medicine
  • Wound repair and regeneration : official…
  • 1 September 2012
Keloid disease (KD) is a fibroproliferative disorder of unknown etiopathogenesis with ill‐defined treatment. There is increasing evidence to suggest that aberrant Notch signaling may contributeExpand
  • 38
  • 4
Degenerate Wave and Capacitive Coupling Increase Human MSC Invasion and Proliferation While Reducing Cytotoxicity in an In Vitro Wound Healing Model
Non-unions pose complications in fracture management that can be treated using electrical stimulation (ES). Bone marrow mesenchymal stem cells (BMMSCs) are essential in fracture healing; however, theExpand
  • 41
  • 4
  • PDF
Exploring the role of stem cells in cutaneous wound healing
Abstract:  The skin offers a perfect model system for studying the wound healing cascade, which involves a finely tuned interplay between several cell types, pathways and processes. The dysregulationExpand
  • 216
  • 3
The role of skin substitutes in the management of chronic cutaneous wounds
Chronic wounds, including diabetic and venous ulcers, represent disruption of normal healing processes resulting in a pathological state of nonhealing cutaneous inflammation. They place anExpand
  • 93
  • 3
  • PDF
Identification of unique gene expression patterns within different lesional sites of keloids
Keloid disease is a significant clinical problem, especially in black populations, with an estimated incidence of 4–16%. Keloids are fibroproliferative dermal tumors developing as a result ofExpand
  • 81
  • 3
Basic fibroblast growth factor: a potential new therapeutic tool for the treatment of hypertrophic and keloid scars.
Numerous tissue niches in the human body, such as skin, are now recognized to harbour adult stem cells. In this study, we analyze multipotent human dermis-derived progenitor cell populations,Expand
  • 54
  • 2