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Molecular interaction between COP1 and HY5 defines a regulatory switch for light control of Arabidopsis development.
TLDR
It is shown that COP1 negatively regulates HY5, a bZIP protein and a positive regulator of photomorphogenic development, and proposed that the direct interaction with and regulation of transcription factors by COP1 may represent the molecular mechanism for its control of gene expression and photomorphic development. Expand
The cryptochromes: blue light photoreceptors in plants and animals.
TLDR
The structural, photochemical, and molecular properties of cry-DASH, plant, and animal cryptochromes are reviewed in relation to biological signaling mechanisms and common features that may contribute to better understanding the function of cryptochromaes in diverse systems including in man are uncovered. Expand
Cryptochrome Blue Light Photoreceptors Are Activated through Interconversion of Flavin Redox States*
TLDR
It is demonstrated that Arabidopsis cryptochrome activation by blue light can be inhibited by green light in vivo consistent with a change of the cofactor redox state, and results indicate that cry1 activation via blue light initiates formation of a flavosemiquinone signaling state that can be converted bygreen light to an inactive form. Expand
The Signaling State of Arabidopsis Cryptochrome 2 Contains Flavin Semiquinone*
TLDR
It is demonstrated that the active form of Cry2 contains FADH· (whereas catalytically active photolyase requires fully reduced flavin (FADH-)) and suggested that cryptochromes could represent photoreceptors using flavin redox states for signaling differently from DNA-photolyase for photorepair. Expand
An Arabidopsis protein closely related to Synechocystis cryptochrome is targeted to organelles.
TLDR
The phylogenetic analyses are consistent with an alternative explanation that the presence of cryptochromes in the plant nuclear genome is the result of dual horizontal gene transfer. Expand
Recognition and repair of UV lesions in loop structures of duplex DNA by DASH-type cryptochrome
TLDR
The crystal structure of Arabidopsis cryptochrome 3 with an in-situ-repaired CPD substrate in single-stranded DNA shows a binding mode similar to that of conventional DNA photolyase, and reveals that DASH cryptochromes catalyze light-driven DNA repair like conventional photolyases but lack an efficient flipping mechanism for interaction with CPD lesions within duplex DNA. Expand
Putative blue-light photoreceptors from Arabidopsis thaliana and Sinapis alba with a high degree of sequence homology to DNA photolyase contain the two photolyase cofactors but lack DNA repair
TLDR
The putative blue-light photoreceptor genes of Arabidopsis thaliana and Sinapis alba (mustard) are highly homologous to the DNA repair genes encoding DNA photolyases, and their chromophore composition suggests that the blue light photoreceptors may initiate signal transduction by a novel pathway which involves electron transfer. Expand
The implication of a plastid-derived factor in the transcriptional control of nuclear genes encoding the light-harvesting chlorophyll a/b protein.
TLDR
The results suggest that, in addition to phytochrome (Pfr), plastid-dependent factors are required for a continuous light-dependent transcription of nuclear genes encoding the LHCP. Expand
Plant blue-light receptors
TLDR
Blue-light photoreceptors of Arabidopsis thaliana (L.) Heynh are presented and there is growing understanding of the primary mechanisms of photore ceptor activation and signal transduction. Expand
Blue-light-induced changes in Arabidopsis cryptochrome 1 probed by FTIR difference spectroscopy.
TLDR
The direct comparison of cryptochrome to photolyase in terms of photoreactivity and mechanism has to be made with caution, as little is known about the pathway from light absorption to signal transduction on the molecular level. Expand
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