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Diterpenoids from Copaifera reticulata Ducke with larvicidal activity against Aedes aegypti (L.) (Diptera, Culicidae).
This study showed that only diterpenoids 1 and 2 exhibited larvicidal properties with LC50 of 0.8 ppm and 87.3 ppm, revealing the former as the most toxic compound against third instars of Ae. Expand
A simple methodology for the determination of fatty acid composition in edible oils through 1H NMR spectroscopy
The methodology was successfully applied to determine the fatty acid composition of several edible oils, with equivalent results to those given by the AOAC Official method by gas chromatography. Expand
Chemical and spectroscopic characterization of humic acids extracted from the bottom sediments of a Brazilian subtropical microbasin
Abstract Humic substances (HS) perform a fundamental role in aquatic environments, exhibiting different levels of reactivity in retaining metal ions and organic pollutants. Also, they control theExpand
Sesquiterpene lactones from Vernonia scorpioides and their in vitro cytotoxicity.
The results indicate that glaucolide 2 and hirsutinolide 4 are toxic to HeLa cells, and these compounds were genotoxic in vitro, a property that appears to be related to the presence of their epoxy groups, which has been a more reliable indication of toxicity than substitution on C-13 or the existence of alpha,beta-unsaturated keto-groups. Expand
Trypanocidal Activity of Oxoaporphine and Pyrimidine-β-Carboline Alkaloids from the Branches of Annona foetida Mart. (Annonaceae)
Phytochemical investigation of the branches of Annona foetida Mart. led to isolation from the CH2Cl2 extract of four alkaloids: Atherospermidine (1), described for the first time in this species,Expand
Evaluation of leishmanicidal and trypanocidal activities of phenolic compounds from Calea uniflora Less.
The phytochemical study of Calea uniflora led to the isolation of nine phenolic compounds identified as noreugenin, ethyl caffeate, which did not present cytotoxic effect towards THP-1 cells, and compound 2 was 3.5-fold more selective than the mixture of 3+4. Expand
In Vitro Atileishmanial and Cytotoxic Activities of Annona mucosa (Annonaceae)
The antileishmanial activity of extracts from the leaves and seeds of Annona mucosa, and of the oxoaporphine alkaloid liriodenine isolated from the dichloromethane extract of the leaves, wereExpand
Chromenes from leaves of Calea pinnatifida and evaluation of their leishmanicidal activity
The isolated chromenes 1 and 3 show a moderate leishmanicidal activity, and the isolated compounds are here reported for the first time in C. pinnatifida. Expand
The phytochemical investigation of the stem bark of Annona pickelii yielded compounds that support their recent reclassification from Rollinia to Annona, and that it is a typical species of the family Annonaceae. Expand
ent-Kaurane diterpenes from the stem bark of Annona vepretorum (Annonaceae) and cytotoxic evaluation.
This work describes a novel ent-kaurane diterpene, ent-3β-hydroxy- kaur-16-en-19-al along with five known ent-Kauranediterpenes, which were evaluated for cytotoxic activities towards tumor B16-F10, HepG2, K562 and HL60 and non-tumor PBMC cell lines. Expand