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Sequence and organization of the human mitochondrial genome
The complete sequence of the 16,569-base pair human mitochondrial genome is presented and shows extreme economy in that the genes have none or only a few noncoding bases between them, and in many cases the termination codons are not coded in the DNA but are created post-transcriptionally by polyadenylation of the mRNAs. Expand
Analysis of the protein-coding content of the sequence of human cytomegalovirus strain AD169.
This chapter is being written in March 1989 when the sequence is complete except for some remaining polishing of certain areas which is still going on (manuscript in preparation). Expand
The genome of the social amoeba Dictyostelium discoideum
A proteome-based phylogeny shows that the amoebozoa diverged from the animal–fungal lineage after the plant–animal split, but Dictyostelium seems to have retained more of the diversity of the ancestral genome than have plants, animals or fungi. Expand
Complete Genome Sequence of the Apicomplexan, Cryptosporidium parvum
Genome analysis identifies extremely streamlined metabolic pathways and a reliance on the host for nutrients in the parasite, which lacks an apicoplast and its genome, and possesses a degenerate mitochondrion that has lost its genome. Expand
DNA sequence and expression of the B95-8 Epstein—Barr virus genome
The complete (172,282 base pairs) nucleotide sequence of the B95-8 strain of Epstein–Barr virus has been established using the dideoxynucleotide/M13 sequencing procedure. Many RNA polymerase IIExpand
The DNA sequence of the human cytomegalovirus genome.
The 229 kilobase pair DNA genome of human cytomegalovirus (HCMV) strain AD169 is the largest contiguous sequence determined to date, and as such provides a realistic benchmark for assessing the practical rate of DNA sequencing as opposed to theoretical calculations which are usually much greater. Expand
The genome of Cryptosporidium hominis
The eight-chromosome ∼9.2-million-base genome of C. hominis shows a striking concordance with the requirements imposed by the environmental niches the parasite inhabits, and phenotypic differences between these parasites must be due to subtle sequence divergence. Expand
Identification of the human cytomegalovirus glycoprotein B gene and induction of neutralizing antibodies via its expression in recombinant vaccinia virus.
Rabbits immunized with the recombinant vaccinia virus produced antibodies that immunoprecipitate gB from HCMV‐infected cells and neutralize H CMV infectivity in vitro, demonstrating a role for this protein in future HCMVs vaccines. Expand
An immediate early gene of human cytomegalovirus encodes a potential membrane glycoprotein.
The sequence of a region of the HCMV genome transcribed during the immediate early (IE) transcriptional phase has been determined and three moderately abundant mRNAs of 3.4, 1.7, and 1.65 kb are identified. Expand