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Consensus on women's health aspects of polycystic ovary syndrome (PCOS): the Amsterdam ESHRE/ASRM-Sponsored 3rd PCOS Consensus Workshop Group.
Ultrasound assessment of the polycystic ovary: international consensus definitions.
Evidence for the current ultrasound definition of the polycystic ovary is outlined and a woman having PCO in the absence of an ovulation disorder or hyperandrogenism ('asymptomatic PCO') should not be considered as having PCOS, until more is known about this situation.
Insulin-sensitising drugs (metformin, rosiglitazone, pioglitazone, D-chiro-inositol) for women with polycystic ovary syndrome, oligo amenorrhoea and subfertility.
- T. Tang, J. Lord, R. Norman, E. Yasmin, A. Balen
- Medicine, BiologyCochrane Database of Systematic Reviews
There is no evidence that metformin improves live birth rates whether it is used alone or in combination with clomiphene, or when compared with clmiphene; therefore, the use of meetformin in improving reproductive outcomes in women with PCOS appears to be limited.
The physiology and clinical utility of anti-Mullerian hormone in women.
There is a linear relationship between AMH and oocyte yield after ovarian stimulation, which is of value in predicting ovarian hyperstimulation, and the submerged part of the iceberg of follicle growth, i.e. the intrinsic, so-called 'acyclic' ovarian activity is measured.
Polycystic ovary syndrome: the spectrum of the disorder in 1741 patients.
Describing data from the largest reported series of women with PCOS enables the development of a management-orientated approach to the syndrome.
Non-invasive amino acid turnover predicts human embryo developmental capacity.
Non-invasive amino acid profiling has the potential to select developmentally competent single embryos for transfer, thereby increasing the success rate and eliminating multiple births in IVF.
Recommendations from the international evidence-based guideline for the assessment and management of polycystic ovary syndrome
Recommendations from the international evidence-based guideline for the assessment and management of polycystic ovary syndrome†‡
The international guideline for the assessment and management of PCOS provides clinicians with clear advice on best practice based on the best available evidence, expert multidisciplinary input and consumer preferences, and emphasizes evidence based medical therapy and cheaper and safer fertility management.
The adverse effects of obesity on conception and implantation.
The effect of obesity upon key reproductive mechanisms and its relation to fertility treatments is discussed and weight loss through lifestyle modification or bariatric surgery has been demonstrated to restore menstrual cyclicity and ovulation and improve the likelihood of conception.
The management of anovulatory infertility in women with polycystic ovary syndrome: an analysis of the evidence to support the development of global WHO guidance.
The consensus guideline methodology is described, the evidence-based recommendations provided to the World Health Organisation (WHO) for their consideration in the development of global guidance are summarised and a narrative review on the management of anovulatory infertility in women with polycystic ovary syndrome is presented.