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Competitive α-glucosidase inhibitors, dihydrobenzoxanthones, from the barks of Artocarpus elasticus
Molecular modelling study proposed the putative binding conformation of competitive inhibitors (1–4) to α-glucosidase at the atomic level and identified two new compounds named as artoindonesianin W and artoflavone B, respectively.
Human neutrophil elastase inhibitory dihydrobenzoxanthones and alkylated flavones from the Artocarpus elasticus root barks
- Y. J. Ban, A. Baiseitova, M. A. Nafiah, Jeong Yoon Kim, K. Park
- ChemistryApplied Biological Chemistry
- 29 September 2020
Neutrophil elastases are deposited in azurophilic granules interspace of neutrophils and tightly associated with inflammatory ailments. The root barks of Artocarpus elasticus had a strong inhibitory…
Tyrosinase inhibitory study of flavonolignans from the seeds of Silybum marianum (Milk thistle).
Effectiveness of Prenyl Group on Flavonoids from Epimedium koreanum Nakai on Bacterial Neuraminidase Inhibition
In this study, the inhibitory potential of bacterial neuraminidase was observed on the leaves of Epimedium koreanum Nakai, which is a popular ingredient in traditional herbal medicine, and affinity constants (KSV) were tightly related to inhibitory activities.
Investigation of chemical constituents of Artemisia absinthium
The aerial part of Artemisia absinthium, collected in Almaty region of Kazakhstan, investigated for chemical constituent with sufficiently completed quantitative and qualitative analysis. Biological…
A Significant Change in Free Amino Acids of Soybean (Glycine max L. Merr) through Ethylene Application
It was found that asparagine is the main component, comprising approximately 41% of the total amino acids with a twenty-five fold increase, and the application of ethylene may provide good nutrient potential for soybean leaves.
Comparative investigation on metabolites changes in soybean leaves by ethylene and activation of collagen synthesis
O-alkylated quercetins with selective acetylcholinesterase and β-secretase inhibitions from Melicope glabra leaves, and their flavonols profile by LC-ESI-Q-TOF/MS
Iridal-Type Triterpenoids Displaying Human Neutrophil Elastase Inhibition and Anti-Inflammatory Effects from Belamcanda chinensis
This is the first report that iridal-type triterpenoids are considered responsible phytochemicals for anti-inflammatory effects of B. chinensis, and among them isoiridogermanal and iridobelamal A displayed significant anti- inflammatory effects by suppressing the expressions of pro-inflammatory cytokines through the NF-κB pathway in LPS-stimulated RAW264.7 cells.
Phytochemical analysis of aerial part of Ikonnikovia kaufmanniana and their protection of DNA damage
- A. Baiseitova, J. Jenis, Jeong Yoon Kim, Zuo Peng Li, K. Park
- ChemistryNatural product research
- 14 May 2019
It was found that Ikonnikovia kaufmanniana, an endemic plant of Kazakhstan, enriched with antioxidant chemicals, had significant antioxidant activity against three radical sources, and their efficacies were found to differ by their functionality and skeleton.